ArticleDiabetology & metabolic syndrome2021
Association of Helicobacter pylori infection with the risk of metabolic syndrome and insulin resistance: an updated systematic review and meta-analysis.
Article in Diabetology & metabolic syndrome, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The association between Helicobacter pylori infection and diabetes mellitus: an updated meta-analysis of 45 case-control studies.Journal of health, population, and nutrition · 2025Pooled it
- Bidirectional relationship betweenFrontiers in nutrition · 2024Pooled it
- Association ofWorld journal of clinical pediatrics · 2026Article
- Impact ofJournal of clinical medicine · 2026Article
- Persistence ofJournal of clinical medicine · 2026Article
- Association Between Metabolic Score for Insulin Resistance and the Incidence of Gastric Cancer in South Korea: A Nationwide Retrospective Study.Journal of clinical medicine · 2026Article
- The association between Helicobacter pylori and osteoporosis: the mediating effect of inflammation.Gut pathogens · 2026Article
- Interaction Between Metabolic Diseases, GLP-1 Receptor Agonists, and Helicobacter pylori Infection: An Updated Evidence Summary.The Korean journal of helicobacter and upper gastrointestinal research · 2026Article
- Association of visceral obesity with Helicobacter pylori seropositivity and mortality in US adults.BMC infectious diseases · 2026Article
- Pathological effects of diabetic mice withWorld journal of diabetes · 2026Article
- Association of TyG and TyG/HDL withFrontiers in medicine · 2026Article
- Immunokinetic signatures ofFrontiers in cellular and infection microbiology · 2026Review
- Interpretable machine learning analysis for relationships betweenFrontiers in cellular and infection microbiology · 2026Article
- Associations ofTherapeutic advances in gastroenterology · 2026Article
- Article
- Article
- Article
- UnravelingVaccines · 2025Review
- Association between serum gastric biomarkers and metabolic syndrome.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundConflicting results of recent studies on the association between Helicobacter pylori (H. pylori) infection and the risk of insulin resistance and metabolic syndrome explored the need for updated meta-analysis on this issue. Therefore, this systematic review aimed to estimate the pooled effect of H. pylori infection on the risk of insulin resistance and metabolic syndrome.
methodsTo identify case-control studies and cohort studies evaluating the association of H. pylori infection with insulin resistance and metabolic syndrome, a comprehensive literature search was performed from international databases including Medline (PubMed), Web of Sciences, Scopus, EMBASE, and CINHAL from January 1990 until January 2021. We used odds ratio with its 95% confidence interval to quantify the effect of case-control studies and risk ratio with its 95% CI for the effect of cohort studies.
results22 studies with 206,911 participants were included for meta-analysis. The pooled estimate of odds ratio between H. pylori infection and metabolic syndrome in case-control studies was 1.19 (95% CI 1.05-1.35; I
conclusionIn this meta-analysis, the results showed that there was a possibility of metabolic syndrome and insulin resistance in case of H. pylori infection.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.