Evidence map›Paper›PMID 34922610›Full record

ArticleTrials2021

Feasibility and effectiveness of prone position ventilation technique for postoperative acute lung injury in infants with congenital heart disease: study protocol for a prospective randomized study.

Yu-Lu Xu, Ya-Ping Mi, Meng-Xin Zhu, Yue-Hong Ren, Wei-Juan Gong, Wei-Jia Fu, Hui-Mei Wang, Lan Ye, Yin Wang, Xiao-Yan Zhou and 7 more

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04607993 (Study on the Effectiveness and Feasibility of Prone Position Ventilation Technique for Postoperative Acute Lung Injury in Infants With Congenital Heart Disease), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04607993 nacompletednot on this map

Study on the Effectiveness and Feasibility of Prone Position Ventilation Technique for Postoperative Acute Lung Injury in Infants With Congenital Heart Disease

TypeinterventionalSponsorChildren's Hospital of Fudan UniversityRan2020 to 2022Enrolled68ConditionsInvestigative TechniquesArmsProne position ventilation technique
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 1 institution in 1 country.

Yu-Lu Xu *Children's Hospital of Fudan University, 399 Wanyuan Road, Minhang District, Shanghai, China.
Ya-Ping Mi *Children's Hospital of Fudan University, 399 Wanyuan Road, Minhang District, Shanghai, China.
Meng-Xin ZhuChildren's Hospital of Fudan University, 399 Wanyuan Road, Minhang District, Shanghai, China.
Yue-Hong RenChildren's Hospital of Fudan University, 399 Wanyuan Road, Minhang District, Shanghai, China.
Wei-Juan GongChildren's Hospital of Fudan University, 399 Wanyuan Road, Minhang District, Shanghai, China.
Wei-Jia FuChildren's Hospital of Fudan University, 399 Wanyuan Road, Minhang District, Shanghai, China.
Hui-Mei WangChildren's Hospital of Fudan University, 399 Wanyuan Road, Minhang District, Shanghai, China.
Lan YeChildren's Hospital of Fudan University, 399 Wanyuan Road, Minhang District, Shanghai, China.
Yin WangChildren's Hospital of Fudan University, 399 Wanyuan Road, Minhang District, Shanghai, China.
Xiao-Yan ZhouChildren's Hospital of Fudan University, 399 Wanyuan Road, Minhang District, Shanghai, China.
Yan ChenChildren's Hospital of Fudan University, 399 Wanyuan Road, Minhang District, Shanghai, China.
Yan-Yan ChenChildren's Hospital of Fudan University, 399 Wanyuan Road, Minhang District, Shanghai, China.
Li-Qiong GuChildren's Hospital of Fudan University, 399 Wanyuan Road, Minhang District, Shanghai, China.
Ying GuChildren's Hospital of Fudan University, 399 Wanyuan Road, Minhang District, Shanghai, China. guying0128@aliyun.com.
Bing JiaChildren's Hospital of Fudan University, 399 Wanyuan Road, Minhang District, Shanghai, China. jiabing2012@hotmail.com.
Jing HuChildren's Hospital of Fudan University, 399 Wanyuan Road, Minhang District, Shanghai, China. hujing1973@yeah.net.
Xiao-Jing HuChildren's Hospital of Fudan University, 399 Wanyuan Road, Minhang District, Shanghai, China. humama2015@126.com.
Children's Hospital of Fudan University · CN

Funding

Fuxing Nursing Research Fund of Fudan University FNF202043
6 · The paper itself

Abstract

backgroundProne position ventilation is a widely used lung protection ventilation strategy. The strategy is more convenient to implement in children compared to adults. Due to the precise mechanism of improving oxygenation function, development of pediatric prone ventilation technology has been largely focused on children with acute respiratory distress syndrome. There is a paucity of high-quality studies investigating the effects of prone position ventilation after pediatric cardiac surgery. The purpose of this study is to evaluate the feasibility and effectiveness of prone position ventilation in infants who develop postoperative acute lung injury after surgery for congenital heart disease.

methodsA single-center, randomized controlled trial of pediatric patients with acute lung injury after surgery for congenital heart disease who will receive prone position ventilation or usual care (control group). A total of 68 children will be enrolled according to the inclusion criteria. The main outcome measures will be lung compliance and oxygenation index. The secondary outcomes will be duration of mechanical ventilation, length of stay in cardiac intensive care unit, reintubation rate, and complication rate. DISCUSSION: This study will investigate the feasibility and effectiveness of prone position ventilation techniques in children who develop postoperative acute lung injury after surgery for congenital heart disease. The results may help inform strategies to improve airway management after surgery for congenital heart disease.

trial registrationClinicalTrials.gov NCT04607993 . Initially registered on 29 October 2020.

Indexed as

Acute Lung InjuryHeart Defects, CongenitalChildFeasibility StudiesHumansInfantLungProne PositionProspective StudiesRandomized Controlled Trials as TopicRespiration, ArtificialCongenital heart diseasePediatricProne position ventilation

Identifiers

PMID34922610
PMCPMC8684128
OpenAlexW4200555011

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.