ReviewAnnals of general psychiatry2021
Prevalence and determinants of depression among old age: a systematic review and meta-analysis.
Review in Annals of general psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 301 papers, 11 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
301 citing papers in PubMed, 11 syntheses or guidelines pooled it, 542 citations in OpenAlex.
- Risk and protective factors associated with depressive symptoms in older adults with visual impairment: a systematic review.The Gerontologist · 2026Pooled it
- Animal-assisted interventions for depression in older adults: an umbrella review with meta-analysis and trial sequential analysis.Aging clinical and experimental research · 2026Pooled it
- Persistent socio-demographic inequalities in depression among older adults in China during and after COVID-19: a systematic review and meta-analysis.Frontiers in public health · 2026Pooled it
- Prevalence and Associated Factors of Chronic Depression Among Older Adults: A Systematic Review, Meta-Analysis, and Meta-Regression.International journal of geriatric psychiatry · 2025Pooled it
- Prevalence of depressive symptoms, anxiety, sleep & substance use disorders among older adults in LMICs: A systematic review & meta-analysis.The Indian journal of medical research · 2025Pooled it
- Metabolomic insights into late-life depression: a systematic review.BMC geriatrics · 2025Pooled it
- Prevalence and Associated Factors of Depression in Nepal: A Systematic Review and Meta-analysis.JNMA; journal of the Nepal Medical Association · 2025Pooled it
- Next-Generation Cognitive-Behavioral Therapy for Depression: Integrating Digital Tools, Teletherapy, and Personalization for Enhanced Mental Health Outcomes.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Predictors and risk factors for suicide in late-life depression: a systematic review and meta-analysis.Frontiers in psychiatry · 2025Pooled it
- Depression in geriatrics: a systematic review and meta-analysis of prevalence and risk factors in Egypt.BMC geriatrics · 2024Pooled it
- Global prevalence of depression, anxiety, and stress in the elderly population: a systematic review and meta-analysis.BMC geriatrics · 2024Pooled it
- Trial
- Interactive Virtual Assistant for Health Promotion Among Older Adults With Type 2 Diabetes: The IVAM-ED Randomized Clinical Trial.JAMA network open · 2026Trial
- Community-based square dancing is associated with improved physical and mental health in older adults: a 12-week randomized controlled trial in China.Frontiers in public health · 2026Trial
- My patient might be depressed - can I still screen for MCI? Exploring cognitive performance on the MoCA in older people screened for depressive symptoms with the PHQ-9.BMC geriatrics · 2025Trial
- Effects of a dual intervention (motor and virtual reality-based cognitive) on cognition in patients with mild cognitive impairment: a single-blind, randomized controlled trial.Journal of neuroengineering and rehabilitation · 2024Trial
- A realist review of the contribution of person-centred cultures to the management of depression among older persons in nursing homes.International journal of nursing studies advances · 2026Review
- Risk of infection in ocrelizumab-treated adults with multiple sclerosis aged 55 years and older: a retrospective cohort study.Lancet regional health. Americas · 2026Article
- Prevalence and correlates of depression among older persons in rural eastern Uganda: a cross-sectional survey.Global health action · 2026Article
- Housing deprivation and depression in older adults living alone: the moderating roles of social capital and urban-rural region.BMC psychology · 2026Article
241 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDepression is a leading cause of disability worldwide and is a major contributor to the overall global burden of disease. It is also one of the most common geriatric psychiatric disorders and a major risk factor for disability and mortality in elderly patients. Even though depression is a common mental health problem in the elderly population, it is undiagnosed in half of the cases. Several studies showed different and inconsistent prevalence rates in the world. Hence, this study aimed to fill the above gap by producing an average prevalence of depression and associated factors in old age.
objectiveThis study aims to conduct a systematic review and meta-analysis to provide a precise estimate of the prevalence of depression and its determinants among old age.
methodA comprehensive search of PubMed, Scopus, Web of sciences, Google Scholar, and Psych-info from database inception to January 2020. Moreover, the reference list of selected articles was looked at manually to have further eligible articles. The random-effects model was employed during the analysis. Stata-11 was used to determine the average prevalence of depression among old age. A sub-group analysis and sensitivity analysis were also run. A graphical inspection of the funnel plots and Egger's publication bias plot test were checked for the occurrence of publication bias.
resultA search of the electronic and manual system resulted in 1263 articles. Nevertheless, after the huge screening, 42 relevant studies were identified, including, for this meta-analysis, n = 57,486 elderly populations. The average expected prevalence of depression among old age was 31.74% (95% CI 27.90, 35.59). In the sub-group analysis, the pooled prevalence was higher among developing countries; 40.78% than developed countries; 17.05%), studies utilized Geriatrics Depression Scale-30(GDS-30); 40.60% than studies that used GMS; 18.85%, study instrument, and studies having a lower sample size (40.12%) than studies with the higher sample; 20.19%.
conclusionA high prevalence rate of depression among the old population in the world was unraveled. This study can be considered as an early warning and advised health professionals, health policymakers, and other pertinent stakeholders to take effective control measures and periodic care for the elderly population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.