ArticleThe journal of headache and pain2021
The relationship between headache-attributed disability and lost productivity: 2. Empirical evidence from population-based studies in nine disparate countries.
Article in The journal of headache and pain, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 27 citations in OpenAlex.
- Factors Associated with Migraine Attack Duration in Adults: A Cross-Sectional Study.Neuroepidemiology · 2026Article
- International Headache Week 2026: March 15-21.The journal of headache and pain · 2026Article
- Occupational Risk for Headache Disorders in Female Registered Nurses. A Retrospective Study.La Medicina del lavoro · 2025Article
- Impact of migraine on productivity and efficiency among adult population in India: a scoping review.The journal of headache and pain · 2025Article
- Impact of Headache and Over-the-Counter Treatment on Pain and Functional and Cognitive Parameters: A Real-World Study across Three Geographies.Pain and therapy · 2025Article
- Anti-CGRP and Anti-CGRP Receptor Monoclonal Antibodies for Migraine Prophylaxis: Retrospective Observational Study on 209 Patients.Journal of clinical medicine · 2024Article
- Debate: differences and similarities between tension-type headache and migraine.The journal of headache and pain · 2023Review
- One Health for Headaches: A Clinical Scientist Residence Project.International journal of environmental research and public health · 2023Article
- The relationship between headache-attributed disability and lost productivity: 3 Attack frequency is the dominating variable.The journal of headache and pain · 2023Article
- Headache in Workers: A Matched Case-Control Study.European journal of investigation in health, psychology and education · 2022Article
- Stigma and Chronic Pain.Pain and therapy · 2022Article
- Reaching the Nadir of Medication Overuse in Chronic Migraine.International journal of environmental research and public health · 2022Article
- Novel Migraine Therapies May Reduce Public and Personal Disadvantages for People with Migraine.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2022Article
- The Global Campaign turns 18: a brief review of its activities and achievements.The journal of headache and pain · 2022Review
- Time is of the essence in headache measurement. A response to Gil-Gouveia.The journal of headache and pain · 2022Article
- The impact of migraine and probable migraine on productivity loss in Korea: A cross-sectional online survey.PloS one · 2022Article
- Structured headache services as the solution to the ill-health burden of headache. 3. Modelling effectiveness and cost-effectiveness of implementation in Europe: findings and conclusions.The journal of headache and pain · 2021Article
- A universal outcome measure for headache treatments, care-delivery systems and economic analysis.The journal of headache and pain · 2021Article
- Editorial. Valuing headache's solution.The journal of headache and pain · 2021Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHeadache disorders are disabling, with major consequences for productivity, yet the literature is silent on the relationship between headache-attributed disability and lost productivity, often erroneously regarding the two as synonymous. We evaluated the relationship empirically, having earlier found that investment in structured headache services would be cost saving, not merely cost-effective, if reductions in headache-attributed disability led to > 20% pro rata recovery of lost productivity.
methodsWe used individual participant data from Global Campaign population-based studies conducted in China, Ethiopia, India, Nepal, Pakistan and Russia, and from Eurolight in Lithuania, Luxembourg and Spain. We assessed relationships in migraine and probable medication-overuse headache (pMOH), the most disabling common headache disorders. Available symptom data included headache frequency, usual duration and usual intensity. We used frequency and duration to estimate proportion of time in ictal state (pTIS). Disability, in the sense used by the Global Burden of Disease study, was measured as the product of pTIS and disability weight for the ictal state. Impairment was measured as pTIS * intensity. Lost productivity was measured as lost days (absence or < 50% productivity) from paid work and corresponding losses from household work over the preceding 3 months. We used Spearman correlation and linear regression analyses.
resultsFor migraine, in a linear model, we found positive associations with lost paid worktime, significant (p < 0.05) in many countries and highly significant (p < 0.001) in some despite low values of R
conclusionRelief of disability through effective treatment of migraine is expected, in most countries, to recover > 20% pro rata of lost productivity, above the threshold for investment in structured headache services to be cost saving.
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