Trial reportJournal of pain and symptom management2022
Clinical Decision Support for Symptom Management in Lung Cancer Patients: A Group RCT.
Trial report in Journal of pain and symptom management, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.
- The use of patient-reported outcome measures to improve patient-related outcomes - a systematic review.Health and quality of life outcomes · 2024Pooled it
- The impact of decision tools during oncological consultation with lung cancer patients: A systematic review within the I3LUNG project.Cancer medicine · 2024Pooled it
- Decision-Making Readiness and Its Influencing Factors Among Lung Cancer Patients Receiving Chemotherapy: A Cross-Sectional Study.Nursing open · 2026Observational
- What Cachexia-Related Outcomes Are Measured in Lung Cancer Chemotherapy Clinical Trials?Cancers · 2025Article
- A qualitative analysis of algorithm-based decision support usability testing for symptom management across the trajectory of cancer care: one size does not fit all.BMC medical informatics and decision making · 2024Article
- Application of IMB model in preventing venous thromboembolism in elderly lung cancer patients.Frontiers in cardiovascular medicine · 2024Article
- Preparation of Self-Assembled, Curcumin-Loaded Nano-Micelles Using Quarternized Chitosan-Vanillin Imine (QCS-Vani Imine) Conjugate and Evaluation of Synergistic Anticancer Effect with Cisplatin.Journal of functional biomaterials · 2023Article
- Application Value of Evidence-Based Care in Patients with Lung Cancer Chemotherapy.Computational and mathematical methods in medicine · 2022Article
- Article
- Exploring the Evolution of Heart Failure Symptoms After Hospitalization and Associations With Social Determinants of Health and Demographic Characteristics.The Journal of cardiovascular nursingObservational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 5 institutions in 1 country.
Funding
Abstract
contextClinical guidelines are available to enhance symptom management during cancer treatment but often are not used in the practice setting. Clinical decision support can facilitate the implementation and adherence to clinical guidelines. and improve the quality of cancer care.
objectivesClinical decision support offers an innovative approach to integrate guideline-based symptom management into oncology care. This study evaluated the effect of clinical decision support-based recommendations on clinical management of symptoms and health-related quality of life (HR-QOL) among outpatients with lung cancer.
methodsTwenty providers and 179 patients were allotted in group randomization to attention control (AC) or Symptom Assessment and Management Intervention (SAMI) arms. SAMI entailed patient-report of symptoms and delivery of recommendations to manage pain, fatigue, dyspnea, depression, and anxiety; AC entailed symptom reporting prior to the visit. Outcomes were collected at baseline, two, four and six-months. Adherence to recommendations was assessed through masked chart review. HR-QOL was measured by the Functional Assessment of Cancer Therapy-Lung questionnaire. Descriptive statistics with linear and logistic regression accounting for the clustering structure of the design and a modified chi-square test were used for analyses.
resultsMedian age of patients was 63 years, 58% female, 88% white, and 32% ≤high school education. Significant differences in clinical management were evident in SAMI vs. AC for all target symptoms that passed threshold. Patients in SAMI were more likely to receive sustained-release opioids for constant pain, adjuvant medications for neuropathic pain, opioids for dyspnea, stimulants for fatigue and mental health referrals for anxiety. However, there were no statistically significant differences in HR-QOL at any time point.
conclusionSAMI improved clinical management for all target symptoms but did not improve patient outcomes. A larger study is warranted to evaluate effectiveness.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.