Evidence map›Paper›PMID 34921874›Full record

ArticleThe Science of the total environment2022

Combined effects of air pollution and extreme heat events among ESKD patients within the Northeastern United States.

Richard V Remigio, Hao He, Jochen G Raimann, Peter Kotanko, Frank W Maddux, Amy Rebecca Sapkota, Xin-Zhong Liang, Robin Puett, Xin He, Amir Sapkota

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Science of the total environment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Harnessing Evolution and Biomimetics to Enhance Planetary Health: Kidney Insights.Journal of the American Society of Nephrology : JASN · 2025
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Richard V RemigioMaryland Institute for Applied Environmental Health, University of Maryland School of Public Health, College Park, MD, USA.
Hao HeDepartment of Atmospheric and Oceanic Sciences, University of Maryland, College Park, MD, USA.
Jochen G RaimannResearch Division, Renal Research Institute, New York, NY, USA.
Peter KotankoResearch Division, Renal Research Institute, New York, NY, USA; Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Frank W MadduxFresenius Medical Care North America, Waltham, MA, USA.
Amy Rebecca SapkotaMaryland Institute for Applied Environmental Health, University of Maryland School of Public Health, College Park, MD, USA.
Xin-Zhong LiangDepartment of Atmospheric and Oceanic Sciences, University of Maryland, College Park, MD, USA; Earth System Science Interdisciplinary Center, University of Maryland, College Park, MD, USA.
Robin PuettMaryland Institute for Applied Environmental Health, University of Maryland School of Public Health, College Park, MD, USA.
Xin HeDepartment of Epidemiology and Biostatistics, University of Maryland School of Public Health, College Park, MD, USA.
Amir SapkotaMaryland Institute for Applied Environmental Health, University of Maryland School of Public Health, College Park, MD, USA. Electronic address: amirsap@umd.edu.

Funding

Unmasking geographic and sociodemographic variability in severe weather-related health risk among end-stage renal disease patientsR36HS027716 · AHRQ · UNIV OF MARYLAND, COLLEGE PARK · PI REMIGIO, RICHARD VICO · 2020 to 2020
$39k
AHRQ HHS R36 HS027716
6 · The paper itself

Abstract

backgroundIncreasing number of studies have linked air pollution exposure with renal function decline and disease. However, there is a lack of data on its impact among end-stage kidney disease (ESKD) patients and its potential modifying effect from extreme heat events (EHE).

methodsFresenius Kidney Care records from 28 selected northeastern US counties were used to pool daily all-cause mortality (ACM) and all-cause hospital admissions (ACHA) counts. County-level daily ambient PM

resultsFrom 2001 to 2016, the sample population consisted of 43,338 ESKD patients. We recorded 5217 deaths and 78,433 hospital admissions. A 10-unit increase in PM

conclusionOur findings suggest interdependent effects of EHE and air pollution among ESKD patients for all-cause mortality risks. National level assessments are needed to consider the ESKD population as a sensitive population and inform treatment protocols during extreme heat and degraded pollution episodes.

Indexed as

Air PollutantsAir PollutionExtreme HeatKidney Failure, ChronicOzoneEnvironmental ExposureHumansParticulate MatterUnited StatesAir PollutantsOzoneParticulate MatterAcute exposuresEffect modificationEnd-stage renal diseaseExtreme heat eventsHemodialysisInteractionOzoneParticulate matter

Identifiers

PMID34921874
PMCPMC8962569

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.