Evidence map›Paper›PMID 34921708›Full record

ArticleJPEN. Journal of parenteral and enteral nutrition2022

Estimated vs measured energy expenditure in ventilated surgical-trauma critically ill patients.

Amir Y Kamel, Laura Robayo, Debbie Liang, Martin D Rosenthal, Chasen A Croft, Gabriela Ghita, Babette Brumback, Philip A Efron, Alicia Mohr, Frederick A Moore and 1 more

Open access · greenAbstract read
In one paragraph

Article in JPEN. Journal of parenteral and enteral nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Longitudinal analysis of caloric requirements in critically ill trauma patients: a retrospective cohort study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Amir Y KamelDepartment of Pharmacy, University of Florida Health Shands Hospital, University of Florida College of Pharmacy, Gainesville, Florida, USA.ORCID 0000-0003-0142-7789
Laura RobayoDepartment of Pharmacy, University of Florida Health Shands Hospital, University of Florida College of Pharmacy, Gainesville, Florida, USA.
Debbie LiangDepartment of Pharmacy, University of North Carolina Healthcare, Raleigh, North Carolina, USA.
Martin D RosenthalDivision of Acute Care Surgery and Center for Sepsis and Critical Illness Research, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA.ORCID 0000-0002-5682-0994
Chasen A CroftDivision of Acute Care Surgery and Center for Sepsis and Critical Illness Research, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA.
Gabriela GhitaDepartment of Biostatistics, College of Public Health and Health Professions, College of Medicine, University of Florida Health Hospital, Gainesville, Florida, USA.
Babette BrumbackDepartment of Biostatistics, College of Public Health and Health Professions, College of Medicine, University of Florida Health Hospital, Gainesville, Florida, USA.
Philip A EfronDivision of Acute Care Surgery and Center for Sepsis and Critical Illness Research, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA.
Alicia MohrDivision of Acute Care Surgery and Center for Sepsis and Critical Illness Research, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA.
Frederick A MooreDivision of Acute Care Surgery and Center for Sepsis and Critical Illness Research, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA.
Scott C BrakenridgeDivision of Acute Care Surgery and Center for Sepsis and Critical Illness Research, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA.
University of Florida · USAdventist University of Health Sciences · USUF Health Shands Hospital · USNorth Carolina State University · US

Funding

PICS: A New Horizon for Surgical Critical CareP50GM111152 · NIGMS · UNIVERSITY OF FLORIDA · PI MOORE, FREDERICK A · 2014 to 2018
$10.7M
NIGMS NIH HHS P50 GM111152
6 · The paper itself

Abstract

backgroundThe American and European guidelines recommend measuring resting energy expenditure (REE) using indirect calorimetry (IC). Predictive equations (PEs) are used to estimate REE, but there is limited evidence for their use in critically ill patients. The aim of this study is to evaluate the degree of agreement and accuracy between IC-measured REE (REE-IC) and 10 different PEs in mechanically ventilated critically ill patients with surgical trauma who met their estimated energy requirement.

methodsREE-IC was retrospectively compared with REE-PE by 10 PEs. The degree of agreement between REE-PE and REE-IC was analyzed by the Bland-Altman test (BAt) and the concordance correlation coefficient (CCC). The accuracy was calculated by the percentage of patients whose REE-PE values differ by up to ±10% in relation to REE-IC. All analyses were stratified by gender and body mass index (BMI; <25 vs ≥25).

resultsWe analyzed 104 patients and the closest estimate to REE-IC was the modified Harris-Benedict equation (mHB) by the BAt with a mean difference of 49.2 overall (61.6 for males, 28.5 for females, 67.5 for BMI <25, and 42.5 for BMI ≥25). The overall CCC between the REE-IC and mHB was 0.652 (0.560 for males, 0.496 for females, 0.570 for BMI <25, and 0.598 for BMI ≥25). The mHB equation was the most accurate with an overall accuracy of 44.2%.

conclusionThe effectiveness of PEs for estimating the REE of mechanically ventilated surgical-trauma critically ill patients is limited. [Correction added on 17 February 2022, after first online publication: The word "with" was deleted before "is limited" in the preceding sentence.] Nonetheless, of the 10 equations examined, the closest to REE-IC was the mHB equation.

Indexed as

Critical IllnessEnergy MetabolismBasal MetabolismCalorimetry, IndirectFemaleHumansMaleNutritional RequirementsReproducibility of ResultsRetrospective Studiescritical illnessestimated caloriesindirect calorimetrymeasured caloriesmechanically ventilatednutritionPredictive Equationssurgerytrauma

Identifiers

PMID34921708
PMCPMC12694736
OpenAlexW4200109718

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.