ReviewJournal of ophthalmic inflammation and infection2021
Multiple evanescent white dot syndrome (MEWDS): update on practical appraisal, diagnosis and clinicopathology; a review and an alternative comprehensive perspective.
Review in Journal of ophthalmic inflammation and infection, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.
What it found
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Who cites it
35 citing papers in PubMed, 3 syntheses or guidelines pooled it, 60 citations in OpenAlex.
- Comprehensive insights into COVID-19 vaccine-associated multiple evanescent white dot syndrome (MEWDS): A systematic analysis of reported cases.Human vaccines & immunotherapeutics · 2024Pooled it
- Differential diagnosis of myopic choroidal neovascularization (mCNV): insights from multimodal imaging and treatment implications.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Pooled it
- The characteristics of white dot syndromes following COVID-19 Vaccines: a systematic review.International ophthalmology · 2024Pooled it
- A case of multiple evanescent white dot syndrome as epiphenomenon of cytomegalovirus infection.American journal of ophthalmology case reports · 2026Article
- From white dot syndromes to primary inflammatory choriocapillaropathies (PICCPs): updating and expanding the spectrum through multimodal imaging.International journal of retina and vitreous · 2026Review
- Multimodal Imaging in Indolent Nonprogressive Multifocal Choroidal Lesions: A Case Report.Cureus · 2026Article
- Article
- Inadequacies in uveitis: misnomers, incongruencies, persistence of obsolete terminologies & inappropriate guidelines, treatment inadequacies, and misinterpretations.Journal of ophthalmic inflammation and infection · 2025Review
- Multiple evanescent white dot syndrome masquerading as atypical optic neuritis: a case report.Journal of medical case reports · 2025Article
- Multiple evanescent white dot syndrome and presentations similar to multiple evanescent white dot syndrome in other disorders: a narrative review.International journal of ophthalmology · 2025Review
- Case report: Two cases of multiple evanescent white dot syndrome with transient night blindness.Frontiers in ophthalmology · 2025Article
- Near-infrared imaging retinal diagnostic applications-a review.International ophthalmology · 2024Review
- Choroidal vasculitis as a biomarker of inflammation of the choroid. Indocyanine Green Angiography (ICGA) spearheading for diagnosis and follow-up, an imaging tutorial.Journal of ophthalmic inflammation and infection · 2024Review
- HLA-A29 Negative Birdshot-like Chorioretinopathy Associated with Vitiligo-Case Report.Journal of clinical medicine · 2024Article
- Infectious eye disease in the 21st century-an overview.Eye (London, England) · 2024Review
- Multiple evanescent white dot syndrome associated with COVID-19 infection: a case report.Journal of medical case reports · 2024Article
- Comparison of clinical findings and subjective symptoms in a case of multiple evanescent white dot syndrome (MEWDS): A case report from a patient's perspective.Journal of general and family medicine · 2024Article
- Atypical multiple evanescent white dot syndrome presenting with peripheral retinal lesions.BMJ case reports · 2024Article
- Fundus Autofluorescence in Posterior and Panuveitis-An Under-Estimated Imaging Technique: A Review and Case Series.Biomolecules · 2024Review
- Multimodal imaging findings of multiple evanescent white dot syndrome in COVID-19 patients.IDCases · 2024Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMultiple evanescent white dot syndrome (MEWDS) is a rare inflammatory eye condition affecting the outer retina as a consequence of choriocapillaris non perfusion. The pathophysiology of MEWDS will be discussed based clinical appraisal and on multimodal imaging appraisal.
methodsNarrative review and perspective opinion.
resultsLiterature review results helped us to put forward (1) the specific symptomatology (decreased/blurred vision, photopsia, subjective scotomas), (2) the ill-asserted character of clinical findings (foveal granularity, white dots in fundoscopy), (3) and the crucial importance of multimodal imaging with the diagnostic triad of ICGA hypofluorescent areas, BL-FAF hyperautofluorescent areas and loss/damage of IS/OS-ellipsoid zone on SD-OCT that characterise the disease and can practically help the clinician to diagnose MEWDS. A comprehensive alternative perspective of the disease was formulated.
conclusionsThe bulk of evidence that we are presenting in this review, thanks to new performing non-invasive and invasive imaging modalities, is sufficiently compelling to consider MEWDS as a primary choriocapillaritis/inflammatory choriocapillaropathy. Multimodal imaging allows the clinician to diagnose MEWDS with a high level of certainty and ensures a precise follow-up.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.