Evidence map›Paper›PMID 34921508›Full record

ArticleInfluenza and other respiratory viruses2022

Respiratory syncytial virus in pediatric influenza-like illness cases in Lombardy, Northern Italy, during seven consecutive winter seasons (from 2014-2015 to 2020-2021).

Laura Pellegrinelli, Cristina Galli, Laura Bubba, Arlinda Seiti, Giovanni Anselmi, Valeria Primache, Lucia Signorini, Serena Delbue, Sandro Binda, Elena Pariani

Abstract read
In one paragraph

Article in Influenza and other respiratory viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Epidemiologic and clinical updates on viral infections in Saudi Arabia.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Article
  7. Observational
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Observational
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Laura PellegrinelliDepartment of Biomedical Sciences for Health, University of Milan, Milan, Italy.ORCID 0000-0003-2344-6032
Cristina GalliDepartment of Biomedical Sciences for Health, University of Milan, Milan, Italy.
Laura BubbaDepartment of Biomedical Sciences for Health, University of Milan, Milan, Italy.
Arlinda SeitiDepartment of Biomedical Sciences for Health, University of Milan, Milan, Italy.
Giovanni AnselmiDepartment of Biomedical Sciences for Health, University of Milan, Milan, Italy.
Valeria PrimacheDepartment of Biomedical Sciences for Health, University of Milan, Milan, Italy.
Lucia SignoriniDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy.
Serena DelbueDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy.
Sandro BindaDepartment of Biomedical Sciences for Health, University of Milan, Milan, Italy.
Elena ParianiDepartment of Biomedical Sciences for Health, University of Milan, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRespiratory syncytial virus (RSV) is the major cause of lower respiratory tract illness in young children and can also cause influenza-like illness (ILI). Here we investigated the epidemiological features of RSV infection in pediatric ILI cases in Lombardy (a region in Northern Italy accounting nearly 10 million inhabitants) from 2014-2015 to 2020-2021 winter seasons. MATERIAL AND

methodsData for this study were retrieved and statistically analyzed from the database of virological influenza surveillance of the regional reference laboratory for Lombardy within the Italian influenza surveillance network (InfluNet).

resultsRSV accounted for nearly 19% of pediatric ILI with a risk of infection nearly two-fold greater than that of individuals ≥15 years. RSV positivity rate increased to 28% considering 0-5 years old children. Although in children ≤5 years the risk of infection from influenza viruses resulted nearly two-fold higher than the risk of RSV infection, the age group 4-6 months and 7-12 months showed a five-fold greater risk of infection from RSV than from influenza. Children ≤5 years of age with pre-existing underlying health conditions had a nearly five-fold greater risk of getting RSV infection than otherwise healthy 0-5 years old children. RSV was identified in ILI cases <15 years of age in all considered winter seasons except in the 2020-2021 season. DISCUSSION: Sentinel surveillance of ILI allowed us to identify groups at higher risk of RSV and influenza infection and to define the start, duration, timing, and intensity of the RSV and influenza community circulation. This surveillance approach can be implemented to assess the RSV circulation and impact in a real-time manner.

Indexed as

Influenza, HumanOrthomyxoviridaeRespiratory Syncytial Virus, HumanRespiratory Syncytial Virus InfectionsChildChild, PreschoolHumansInfantInfant, NewbornSeasonsinfluenza-like illnessinfluenza surveillancerespiratory syncytial virus (RSV)risk of infection children

Identifiers

PMID34921508
PMCPMC8983902

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.