Evidence map›Paper›PMID 34921443›Full record

ReviewJournal of clinical laboratory analysis2022

Recent advances in methods for the diagnosis of Corona Virus Disease 2019.

Jie Guo, Jiaxin Ge, Yanan Guo

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical laboratory analysis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
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  5. Observational
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. [Molecular biology in a blood bank].Revista medica del Instituto Mexicano del Seguro Social · 2023
    Review
  14. [PCR for COVID in the transplant protocol].Revista medica del Instituto Mexicano del Seguro Social · 2023
    Observational
  15. Importance of external quality assessment for SARS-CoV-2 antigen detection during the COVID-19 pandemic.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2022
    Article
  16. Article
  17. Article
  18. Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jie GuoState Key Laboratory Base of Novel Functional Materials and Preparation Science, School of Materials Science & Chemical Engineering, Ningbo University, Ningbo, China.ORCID https://orcid.org/0000-0002-5584-5292
Jiaxin GeDepartment of Gastroenterology, the Affiliated Hospital of Ningbo University School of Medicine, Ningbo, China.
Yanan GuoDepartment of Experimental Pathology, Ningbo Clinical Pathology Diagnosis Center, Ningbo, China.
Ningbo University · CNUniversity of Nottingham Ningbo China · CN

Funding

The K. C. Wong Magna Fund in Ningbo University
6 · The paper itself

Abstract

Since the beginning of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic, it has been clear that effective methods for the diagnosis of Corona Virus Disease 2019 (COVID-19) are the key tools to control its epidemic. The current gold standard for diagnosing COVID-19 is the real-time quantitative reverse transcription-polymerase chain reaction (qRT-PCR), which is a sensitive and specific method to detect SARS-CoV-2. Other RNA-based methods include RNA sequencing (RNA-seq), droplet digital reverse transcription-polymerase chain reaction (ddRT-PCR), reverse transcription loop-mediated isothermal amplification (RT-LAMP), and clustered regularly interspaced short palindromic repeats (CRISPR). The serological testing of antibodies (IgM and IgG), nanoparticle-based lateral-flow assay, and enzyme-linked immunosorbent assay (ELISA) can be used to enhance the detection sensitivity and accuracy. Because antibodies are usually detected a week after the onset of symptoms, these tests are used to assess the overall infection rate in the community. Sine the fact that healthcare varies from country to country across the world, different types of diagnosing COVID-19 imaging technologies including chest computed tomography (CT), chest radiography, and lung ultrasound are used in different degrees. Besides, the pooling test is an important public health tool to reduce cost and increase testing capacity in low-risk area, while artificial intelligence (AI) may aid to increase the diagnostic efficiency of imaging-based methods. Finally, depending on the type of samples and stages of the disease, a combination of information on patient demographics and histories, clinical symptoms, results of molecular and serological diagnostic tests, and imaging information is highly recommended to achieve adequate diagnosis of patients with COVID-19.

Indexed as

Antibodies, ViralClustered Regularly Interspaced Short Palindromic RepeatsCOVID-19COVID-19 Nucleic Acid TestingCOVID-19 Serological TestingEnzyme-Linked Immunosorbent AssayHumansMolecular Diagnostic TechniquesNucleic Acid Amplification TechniquesReal-Time Polymerase Chain ReactionRNA-SeqRNA, ViralSARS-CoV-2Sensitivity and SpecificityAntibodies, ViralRNA, ViralCOVID-19diagnosisreverse transcription-polymerase chain reactionSARS-CoV-2

Identifiers

PMID34921443
PMCPMC8761393
OpenAlexW4200317011

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.