Evidence map›Paper›PMID 34921314›Full record

SynthesisNutrition reviews2022

Reducing salt intake: a systematic review and meta-analysis of behavior change interventions in adults.

Saman Khalesi, Edwina Williams, Christopher Irwin, David W Johnson, Jacqui Webster, Danielle McCartney, Arash Jamshidi, Corneel Vandelanotte

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Nutrition reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
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  8. Article
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  12. Observational
  13. Ecological momentary assessment of meal context and food types contributing to salt intake at meals.The international journal of behavioral nutrition and physical activity · 2025
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. High Salt Promotes Inflammatory and Fibrotic Response in Peritoneal Cells.International journal of molecular sciences · 2023
    Article
  20. Disparities in transitions of acute stroke care: The transitions of care stroke disparities study methodological report.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2023
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Saman KhalesiAppelton Institute & School of Health, Medical and Applied Sciences, Central Queensland University, Rockhampton & Brisbane, Queensland, Australia.ORCID 0000-0002-8208-2518
Edwina WilliamsAppelton Institute & School of Health, Medical and Applied Sciences, Central Queensland University, Rockhampton & Brisbane, Queensland, Australia.
Christopher IrwinMenzies Health Institute Queensland and School of Health Sciences and Social Work, Griffith University, Gold Coast, Queensland, Australia.
David W JohnsonCentre for Kidney Disease Research, University of Queensland, Brisbane, Queensland, Australia.
Jacqui WebsterThe George Institute for Global Health, University of New South Wales, Sydney, New South Wales, Australia.ORCID 0000-0003-3513-3340
Danielle McCartneyFaculty of Science, School of Psychology, University of Sydney, Sydney, New South Wales, Australia.
Arash JamshidiInfoClin Inc, Ontario, Toronto, Canada.
Corneel VandelanotteAppelton Institute & School of Health, Medical and Applied Sciences, Central Queensland University, Rockhampton & Brisbane, Queensland, Australia.ORCID 0000-0002-4445-8094
Central Queensland University · AUGriffith University · AUThe University of Sydney · AUTranslational Research Institute · AUUNSW Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextProlonged high salt (sodium) intake can increase the risk of hypertension and cardiovascular disease. Behavioral interventions may help reduce sodium intake at the population level.

objectiveThe effectiveness of behavior change interventions to reduce sodium intake in adults was investigated in this systematic review and meta-analysis. DATA SOURCE: The PubMed, Cochrane Library, Cumulative Index to Nursing and Allied Health Literature, and EMBASE databases were searched. DATA EXTRACTION: Narrative synthesis and random-effects meta-analyses were used to determine intervention efficacy. A total of 61 trials (46 controlled trials and 15 quasi-experimental studies) were included.

resultsBehavior change interventions resulted in significant improvements in salt consumption behavior (eg, decrease in purchase of salty foods; increase in use of salt substitutes), leading to reductions in sodium intake as measured by urinary sodium in 32 trials (N = 7840 participants; mean difference, -486.19 mg/d [95%CI, -669.44 to -302.95]; P < 0.001; I2 = 92%) and dietary sodium in 19 trials (N = 3750 participants; mean difference -399.86 mg/d [95%CI, -581.51 to -218.20]; P < 0.001; I2 = 96%), equivalent to a reduction of >1 g of salt intake daily. Effects were not significantly different based on baseline sodium intakes, blood pressure status, disease status, the use of behavior change theories, or the main method of intervention delivery (ie, online vs face-to-face).

conclusionBehavior change interventions are effective at improving salt consumption practices and appear to reduce salt intake by >1 g/d. SYSTEMATIC REVIEW REGISTRATION: PROSPERO registration no. CRD42020185639.

Indexed as

Cardiovascular DiseasesHypertensionAdultBlood PressureFeeding BehaviorHumansSodium Chloride, DietarySodium Chloride, Dietarybehavior modificationdiethypertensionsalt intake

Identifiers

PMID34921314
PMCPMC8907486
OpenAlexW4200122737

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.