ArticleThe ISME journal2022
Diel investments in metabolite production and consumption in a model microbial system.
Article in The ISME journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Article
- Characterization of phytoplankton-excreted metabolites mediating carbon flux through the surface ocean.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Diel and eddy driven changes in microbial gene expression and biogeochemistry in the oceanic chlorophyll maximum.Nature communications · 2026Article
- Dynamic reworking of marine diatom endometabolomes in response to temperature and a model bacterium.mSystems · 2026Article
- Diel study reveals increased nighttime bacterial activity and its connection to organic compounds in the ocean.Communications biology · 2025Article
- Chemotaxis, growth, and inter-species interactions shape early bacterial community assembly.The ISME journal · 2025Article
- Diatom volatile organic compound production is driven by diel metabolism and the cell cycle.Frontiers in microbiology · 2025Article
- Overlooked Vital Role of Persistent Algae-Bacteria Interaction in Ocean Recalcitrant Carbon Sequestration and Its Response to Ocean Warming.Global change biology · 2024Article
- Digital Microbe: a genome-informed data integration framework for team science on emerging model organisms.Scientific data · 2024Article
- Microbiome and photoperiod interactively determine thermal sensitivity of polar and temperate diatoms.Biology letters · 2023Article
- Daily turnover of active giant virus infection during algal blooms revealed by single-cell transcriptomics.Science advances · 2023Article
- Biogeographic patterns of biosynthetic potential and specialized metabolites in marine sediments.The ISME journal · 2023Article
- Ecological divergence of syntopic marine bacterial species is shaped by gene content and expression.The ISME journal · 2023Article
- Microbial metabolites in the marine carbon cycle.Nature microbiology · 2022Review
- Growth-stage-related shifts in diatom endometabolome composition set the stage for bacterial heterotrophy.ISME communications · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Organic carbon transfer between surface ocean photosynthetic and heterotrophic microbes is a central but poorly understood process in the global carbon cycle. In a model community in which diatom extracellular release of organic molecules sustained growth of a co-cultured bacterium, we determined quantitative changes in the diatom endometabolome and the bacterial uptake transcriptome over two diel cycles. Of the nuclear magnetic resonance (NMR) peaks in the diatom endometabolites, 38% had diel patterns with noon or mid-afternoon maxima; the remaining either increased (36%) or decreased (26%) through time. Of the genes in the bacterial uptake transcriptome, 94% had a diel pattern with a noon maximum; the remaining decreased over time (6%). Eight diatom endometabolites identified with high confidence were matched to the bacterial genes mediating their utilization. Modeling of these coupled inventories with only diffusion-based phytoplankton extracellular release could not reproduce all the patterns. Addition of active release mechanisms for physiological balance and bacterial recognition significantly improved model performance. Estimates of phytoplankton extracellular release range from only a few percent to nearly half of annual net primary production. Improved understanding of the factors that influence metabolite release and consumption by surface ocean microbes will better constrain this globally significant carbon flux.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.