Evidence map›Paper›PMID 34921271›Full record

ArticleBritish dental journal2021

Understanding dental caries as a non-communicable disease.

Nigel B Pitts, Svante Twetman, Julian Fisher, Philip D Marsh

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in British dental journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 162 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
162citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

162 citing papers in PubMed, 9 syntheses or guidelines pooled it.

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  3. Exploring potential salivary biomarkers for dental caries: a systematic review.Medicina oral, patologia oral y cirugia bucal · 2025
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  16. Characterizing the supragingival microbiome of healthy pregnant women.Frontiers in cellular and infection microbiology · 2022
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102 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nigel B PittsFaculty of Dentistry, Oral & Craniofacial Sciences, King´s College London, Tower Wing, Guy´s Hospital, London, SE1 9RT, UK.
Svante TwetmanDepartment of Odontology, Faculty of Health and Medical Sciences, University of Copenhagen, Nørre Alle 20, 2200 Copenhagen N, Denmark. stwe@sund.ku.dk.
Julian FisherDepartment of Oral Diagnostics, Digital Health and Health Services Research, CharitéCentrum 3 für Zahnmedizin, Charité-Universitätsmedizin Berlin, Aβmannshauser Str 4-6, 14197 Berlin, Germany.
Philip D MarshDepartment of Oral Biology, School of Dentistry, University of Leeds, Leeds, LS2 7TF, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recent developments in the science underpinning our knowledge of both the initiation of dental caries and the subsequent behaviour of lesions over time gives us a solid base to understand caries differently. Advances in understanding the human and oral microbiome have come in parallel with the recognition of the importance of balancing protective and pathological risk factors. Caries prevention and management is now about controlling risk factors to maintain a balanced intraoral biofilm ecology that guards against a continuing low pH driven by the frequent consumption of sugars. Thus, caries control is no longer about attempts at eradicating any specific microorganism. Further, the present knowledge leads to the classification of dental caries as a non-communicable disease (NCD), which is vitally important from a policy perspective (both globally and at the country level). Caries shares similar risk factors with other chronic/systemic diseases, which provides opportunities for developing common prevention strategies and promoting health equity through action on the social determinants of health. So, preventing and controlling caries should be integrated across the so-called upstream, midstream and downstream levels and these activities can also help to control other NCDs.

Indexed as

Dental CariesMicrobiotaNoncommunicable DiseasesBiofilmsHumansSugarsSugars

Identifiers

PMID34921271
PMCPMC8683371

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.