SynthesisLupus science & medicine2021
Incidence rates of systemic lupus erythematosus in the USA: estimates from a meta-analysis of the Centers for Disease Control and Prevention national lupus registries.
Synthesis in Lupus science & medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Identification of genetic variants in B cell expressed genes associated with systemic lupus erythematosus in African American females.ImmunoHorizons · 2026Article
- Increasing the utilisation of hydroxychloroquine blood level testing in lupus: a quality improvement project.Lupus science & medicine · 2026Article
- The fourth trimester and challenges for the lupus patient.EULAR rheumatology open · 2025Review
- A Systemic Lupus Erythematosus Incidence Surveillance Report Among DoD Beneficiaries During the COVID-19 Pandemic.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2025Article
- Leveraging undecided cases in chart-reviewed phenotypes to enhance EHR-based association studies.Journal of biomedical informatics · 2025Article
- Review
- Evaluation and Bias Analysis of Large Language Models in Generating Synthetic Electronic Health Records: Comparative Study.Journal of medical Internet research · 2025Article
- Meeting report: The Systemic Lupus International Collaborating Clinics (SLICC) World Lupus Seminar on Africa.Lupus science & medicine · 2025Article
- Racial differences in clinical trial perceptions among a large, predominantly Black cohort of people with systemic lupus erythematosus in the Southeastern USA.Lupus science & medicine · 2025Article
- Mapping the spatial and temporal frequency of systemic lupus erythematosus in Brazil.Revista brasileira de epidemiologia = Brazilian journal of epidemiology · 2025Article
- The Impact of Self-Management Interventions on Behavioral and Clinical Outcomes in Individuals with Systemic Lupus Erythematosus: A Systematic Review of Empirical Evidence From 2003-2024.Patient preference and adherence · 2025Review
- Prevalence of cardiovascular events in a population-based registry of patients with systemic lupus erythematosus.Arthritis research & therapy · 2024Article
- Article
- Financial Hardship and Sleep Quality Among Black American Women With and Without Systemic Lupus Erythematosus.Psychosomatic medicine · 2024Article
- Pulmonary Hypertension in Underrepresented Minorities: A Narrative Review.Journal of clinical medicine · 2024Review
- Gender-Related Characterization of Acne in Chinese: A Multiple-Center Cross-Sectional Survey on 13085 Cases.Clinical, cosmetic and investigational dermatology · 2024Article
- Associations between CD70 methylation of T cell DNA and age in adults with systemic lupus erythematosus and population controls: The Michigan Lupus Epidemiology & Surveillance (MILES) Program.Journal of autoimmunity · 2024Article
- Prevalence of concomitant rheumatologic diseases and autoantibody specificities among racial and ethnic groups in SLE patients.Frontiers in epidemiology · 2024Article
- Rehabilitation in Systemic Lupus Erythematosus With Class 4 Lupus Nephritis Secondary to Pneumonia: A Case Report.Cureus · 2023Article
- Population-based prevalence and incidence estimates of mixed connective tissue disease from the Manhattan Lupus Surveillance Program.Rheumatology (Oxford, England) · 2023Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
objectiveTo estimate the annual incidence rate of SLE in the USA.
methodsA meta-analysis used sex/race/ethnicity-specific data spanning 2002-2009 from the Centers for Disease Control and Prevention network of four population-based state registries to estimate the incidence rates. SLE was defined as fulfilling the 1997 revised American College of Rheumatology classification criteria. Given heterogeneity across sites, a random effects model was employed. Applying sex/race/ethnicity-stratified rates, including data from the Indian Health Service registry, to the 2018 US Census population generated estimates of newly diagnosed SLE cases.
resultsThe pooled incidence rate per 100 000 person-years was 5.1 (95% CI 4.6 to 5.6), higher in females than in males (8.7 vs 1.2), and highest among black females (15.9), followed by Asian/Pacific Islander (7.6), Hispanic (6.8) and white (5.7) females. Male incidence was highest in black males (2.4), followed by Hispanic (0.9), white (0.8) and Asian/Pacific Islander (0.4) males. The American Indian/Alaska Native population had the second highest race-specific SLE estimates for females (10.4 per 100 000) and highest for males (3.8 per 100 000). In 2018, an estimated 14 263 persons (95% CI 11 563 to 17 735) were newly diagnosed with SLE in the USA.
conclusionsA network of population-based SLE registries provided estimates of SLE incidence rates and numbers diagnosed in the USA.
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