Evidence map›Paper›PMID 34921076›Full record

ArticleBMJ open2021

Brazilian network of COVID-19 during pregnancy (REBRACO: a multicentre study protocol).

Maria Laura Costa, Renato T Souza, Rodolfo C Pacagnella, Silvana F Bento, Carolina C Ribeiro-do-Valle, Adriana G Luz, Giuliane J Lajos, Silvia B Mazon, Luis Bahamondes, Fernanda G Surita and 24 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. Gamma SARS-CoV-2 variant of concern infection repercussions on pregnancy outcomes: A translational cohort study.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Article
  2. Article
  3. Article
  4. Five years after the COVID-19 pandemic began: lessons on vaccination and obstetric care in Brazil.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025
    Article
  5. Placentas From SARS-CoV-2 Infection During Pregnancy Exhibit Foci of Oxidative Stress and DNA Damage.American journal of reproductive immunology (New York, N.Y. : 1989) · 2025
    Article
  6. Brazilian Black Women are at Higher Risk for COVID-19 Complications: An Analysis of REBRACO, a National Cohort.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2023
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors at 11 institutions in 1 country.

Maria Laura CostaSchool of Medical Sciences. Department of Obstetrics and Gynaecology, State University of Campinas Faculty of Medical Sciences, Campinas, Brazil mlaura@unicamp.br.ORCID 0000-0001-8280-3234
Renato T SouzaDepartment of Obstetrics and Gynaecology, State University of Campinas Faculty of Medical Sciences, Campinas, Brazil.
Rodolfo C PacagnellaDepartment of Obstetrics and Gynaecology, State University of Campinas Faculty of Medical Sciences, Campinas, Brazil.
Silvana F BentoDepartment of Obstetrics and Gynecology, State University of Campinas Faculty of Medical Sciences, Campinas, Brazil.
Carolina C Ribeiro-do-ValleDepartment of Obstetrics and Gynecology, State University of Campinas Faculty of Medical Sciences, Campinas, Brazil.
Adriana G LuzObstetrics and Gineacology, State University of Campinas Faculty of Medical Sciences, Campinas, Brazil.
Giuliane J LajosObstetrics and Gineacology, State University of Campinas Faculty of Medical Sciences, Campinas, Brazil.
Silvia B MazonDepartment of Obstetrics and Gynecology, State University of Campinas Faculty of Medical Sciences, Campinas, Brazil.
Luis BahamondesDepartment of Obstetrics and Gynecology, State University of Campinas Faculty of Medical Sciences, Campinas, Brazil.
Fernanda G SuritaObstetrics and Gyneacology, State University of Campinas Faculty of Medical Sciences, Campinas, Brazil.ORCID 0000-0003-4335-0337
Guilherme M NobregaDepartment of Obstetrics and Gynecology, State University of Campinas Faculty of Medical Sciences, Campinas, Brazil.ORCID 0000-0001-9406-4256
Thayna B GriggioDepartment of Obstetrics and Gynecology, State University of Campinas Faculty of Medical Sciences, Campinas, Brazil.
Charles M'poca CharlesDepartment of Obstetrics and Gynaecology, State University of Campinas Faculty of Medical Sciences, Campinas, Brazil.ORCID 0000-0001-7133-0574
Maria J MieleDepartment of Obstetrics and Gynecology, State University of Campinas Faculty of Medical Sciences, Campinas, Brazil.
Ricardo P TedescoDepartment of Obstetrics and Gynecology, Faculdade de Medicina de Jundiai, Jundiai, Brazil.
Karayna G FernandesDepartment of Obstetrics and Gynecology, State University of Campinas Faculty of Medical Sciences, Campinas, Brazil.
Sergio Martins-CostaDepartment of Obstetrics and Gynecology, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Frederico Ja PeretDepartment of Obstetrics and Gynecology, Unimed Belo Horizonte, Belo Horizonte, Brazil.
Francisco E FeitosaDepartment of Obstetrics and Gynecology, Sociedade de Assistencia a Maternidade Escola Assis Chateaubriand, Fortaleza, Brazil.
Rosiane MattarDepartment of Obstetrics and Gynecology, UNIFESP, Sao Paulo, Brazil.
Evelyn TrainaDepartment of Obstetrics and Gynecology, UNIFESP, Sao Paulo, Brazil.
Edson V Cunha FilhoDepartment of Obstetrics and Gynecology, Hospital Moinhos de Vento, Porto Alegre, Brazil.
Janete VettorazziDepartment of Obstetrics and Gynecology, Hospital Moinhos de Vento, Porto Alegre, Brazil.
Samira M HaddadDepartment of Obstetrics and Gynecology, State University of Campinas Faculty of Medical Sciences, Campinas, Brazil.
Carla B AndreucciDepartment of Obstetrics and Gynecology, UFSCar, Sao Carlos, Brazil.
José Paulo GuidaDepartment of Obstetrics and Gynecology, State University of Campinas, Campinas, Brazil.
Mario D Correa JuniorDepartment of Obstetrics and Gynecology, UFMG, Belo Horizonte, Brazil.
Marcos Augusto Bastos DiasDepartment of Obstetrics, Instituto Fernandes Figueira, Rio de Janeiro, Brazil.
Leandro G OliveiraDepartment of Obstetrics and Gynecology, UNESP Campus de Botucatu, Botucatu, Brazil.
Elias F Melo JuniorUniversity of Pernambuco, Recife, Brazil.
Carlos As MenezesObstetrics and Gyneacology, Salvador University, Salvador, BA, Brazil.
Marília Gq LuzSanta Casa de Misericórdia do Pará, Belem, Pará, Brazil.
Jose Guilherme CecattiDepartment of Obstetrics and Gynecology, State University of Campinas Faculty of Medical Sciences, Campinas, Brazil.ORCID 0000-0003-1285-8445
REBRACO Study Group
Universidade Estadual de Campinas (UNICAMP) · BRFundação de Apoio à Universidade Federal de São Paulo · BRHospital Moinhos de Vento · BRCentro Universitário de Belo Horizonte · BRFaculdade de Medicina de Jundiaí · BRUniversidade de Pernambuco · BRUniversidade Estadual Paulista (Unesp) · BRUniversidade Federal de Minas Gerais · BRUniversidade Federal de São Carlos · BRUniversidade Federal do Rio Grande do Sul · BRUniversidade Salvador · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe aim of this study was to evaluate the clinical, epidemiological and laboratory aspects of SARS-CoV-2 infection during pregnancy and postpartum in 16 maternity hospitals. METHODS AND ANALYSIS: A prospective multicentre study, with five axes. First, the prevalence of SARS-CoV-2 infection among women admitted for childbirth will be described in a cross-sectional study. Second, maternal and perinatal outcomes will be assessed in a prospective cohort study including pregnant or postpartum women with suspected COVID-19. Third, a cohort of positive COVID-19 cases with sampling of a variety of biological material. Histopathological and viral analysis of biological maternal and neonatal samples will be performed, and the assessment of nutritional variables to evaluate the association between vitamin D and severity of infection. Fourth, a monitoring and evaluation committee to collect relevant healthcare information and plan actions in centres facing the pandemic. Furthermore, qualitative studies will be performed to study pregnant women, their families and health professionals. Fifth, an ecological study will monitor the number of live births, stillbirths and other outcomes to explore any trend among the periods before, during and after the pandemic. Data will systematically be collected in an electronic platform following standardised operational procedures. For quantitative study components, an appropriate statistical approach will be used for each analysis. For qualitative data, in-depth interviews recorded in audio will be transcribed, checking the text obtained with the recording. Subsequently, thematic analysis with the aid of the NVivo programme will be performed. ETHICS AND DISSEMINATION: Ethical approval was obtained (letters of approval numbers 4.047.168, 4.179.679 and 4.083.988). All women will be fully informed to sign the consent form before enrolment in the study. Findings will be disseminated through peer-reviewed journals and scientific conferences.

Indexed as

COVID-19Cross-Sectional StudiesFemaleHumansInfant, NewbornMulticenter Studies as TopicParturitionPregnancyProspective StudiesSARS-CoV-2COVID-19infection controlmaternal medicineprenatal diagnosisqualitative research

Identifiers

PMID34921076
PMCPMC8685531
OpenAlexW4200569819

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.