Evidence map›Paper›PMID 34920940›Full record

ArticleZeitschrift fur medizinische Physik2022

An MRI sequence independent convolutional neural network for synthetic head CT generation in proton therapy.

Lukas Zimmermann, Barbara Knäusl, Markus Stock, Carola Lütgendorf-Caucig, Dietmar Georg, Peter Kuess

Open access · hybridAbstract read
In one paragraph

Article in Zeitschrift fur medizinische Physik, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Recent advances in applying machine learning to proton radiotherapy.Biomedical physics & engineering express · 2025
    Pooled it
  2. Deep learning in MRI-guided radiation therapy: A systematic review.Journal of applied clinical medical physics · 2024
    Pooled it
  3. Pooled it
  4. Deep Learning for CT Synthesis in Radiotherapy.Bioengineering (Basel, Switzerland) · 2025
    Review
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  8. Feasibility of direct brainAsia Oceania journal of nuclear medicine & biology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Lukas ZimmermannMedical University of Vienna, Department of Radiation Oncology, Vienna, Austria; Faculty of Engineering, University of Applied Sciences Wiener Neustadt, Austria; Competence Center for Preclinical Imaging and Biomedical Engineering, University of Applied Sciences Wiener Neustadt, Austria.
Barbara KnäuslMedical University of Vienna, Department of Radiation Oncology, Vienna, Austria; MedAustron Ion Therapy Center, Wiener Neustadt, Austria.
Markus StockMedAustron Ion Therapy Center, Wiener Neustadt, Austria.
Carola Lütgendorf-CaucigMedAustron Ion Therapy Center, Wiener Neustadt, Austria.
Dietmar GeorgMedical University of Vienna, Department of Radiation Oncology, Vienna, Austria.
Peter KuessMedical University of Vienna, Department of Radiation Oncology, Vienna, Austria; MedAustron Ion Therapy Center, Wiener Neustadt, Austria. Electronic address: peter.kuess@meduniwien.ac.at.
MedAustron · ATFachhochschule Wiener Neustadt · ATMedical University of Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A magnetic resonance imaging (MRI) sequence independent deep learning technique was developed and validated to generate synthetic computed tomography (sCT) scans for MR guided proton therapy. 47 meningioma patients previously undergoing proton therapy based on pencil beam scanning were divided into training (33), validation (6), and test (8) cohorts. T

Indexed as

Proton TherapyHeadHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingNeural Networks, ComputerRadiotherapy Planning, Computer-AssistedTomography, X-Ray ComputedMRI-onlyProton therapySynthetic CTTransfer learning

Identifiers

PMID34920940
PMCPMC9948837
OpenAlexW4200383844

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.