Evidence map›Paper›PMID 34920744›Full record

ArticleJournal of medical case reports2021

Osteonecrosis of the humeral head in a human immunodeficiency virus-infected patient under tenofovir disoproxil fumarate-emtricitabine-lopinavir/ritonavir for 10 years: a case report.

Kalilou Diallo, Bruce Shinga Wembulua, Mohamadou Aidara, Armel Alleyo, Noel Magloire Manga

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of medical case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Aseptic osteonecrosis of the jaw in a patient with HIV on tenofovir.Proceedings (Baylor University. Medical Center) · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kalilou DialloUnit of Infectious and Tropical Diseases, Assane Seck University, Hospital de la Paix, Ziguinchor, Senegal.
Bruce Shinga WembuluaDepartment of Infectious and Tropical Diseases, Fann University Hospital, Dakar, Senegal. bruliawems@gmail.com.ORCID http://orcid.org/0000-0001-6639-5648
Mohamadou AidaraUnit of Radiology, Hospital de la Paix, Ziguinchor, Senegal.
Armel AlleyoUnit of Orthopedics and Traumatology, Hospital de la Paix, Ziguinchor, Senegal.
Noel Magloire MangaUnit of Infectious and Tropical Diseases, Assane Seck University, Hospital de la Paix, Ziguinchor, Senegal.
Ziguinchor University · SNCentre Hospitalier National Universitaire de Fann · SN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHuman immunodeficiency virus-infected patients are 100 times more likely to develop aseptic osteonecrosis compared with the general population. While 90% of cases concern the femoral head, the involvement of humeral bone remains rare. CASE PRESENTATION: We report a case of aseptic osteonecrosis of the left humeral head complicating antiretroviral therapy in a female, 46-year-old, Bissau-Guinean human immunodeficiency virus-infected patient received in a context of progressive pain in the left shoulder followed by limitation of articular movements. Standard x-ray of the shoulder allowed us to make the diagnosis by showing a typical image of osteonecrosis. The treatment was medical combined with physiotherapy.

conclusionsAseptic osteonecrosis should be systematically looked for in human immunodeficiency virus patients on antiretroviral treatment. In addition to femoral head aseptic necrosis, the involvement of the humeral bone should also be considered.

Indexed as

HIV InfectionsOsteonecrosisEmtricitabineFemaleHIVHumansHumeral HeadLopinavirMiddle AgedRitonavirTenofovirEmtricitabineLopinavirRitonavirTenofovirAntiretroviral therapyAseptic osteonecrosisCase reportHIV-infected patientsHumeral head

Identifiers

PMID34920744
PMCPMC8684112
OpenAlexW4200125062

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.