Evidence map›Paper›PMID 34920115›Full record

ArticleJournal of clinical epidemiology2022

COVID-19 vaccine guidelines was numerous in quantity but many lack transparent reporting of methodological practices.

Zijun Wang, Hui Liu, Yang Li, Xufei Luo, Nan Yang, Meng Lv, Qi Zhou, Qinyuan Li, Ling Wang, Junxian Zhao and 10 more

Abstract read
In one paragraph

Article in Journal of clinical epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Observational
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Zijun WangEvidence-based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China; Lanzhou University Institute of Health Data Science, Lanzhou, China.
Hui LiuSchool of Public Health, Lanzhou University, Lanzhou, China.
Yang LiDepartment of Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, National Medical Center for Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China.
Xufei LuoSchool of Public Health, Lanzhou University, Lanzhou, China.
Nan YangEvidence-based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.
Meng LvDepartment of Nephrology, Children's Hospital of Chongqing Medical University, Chongqing, China.
Qi ZhouEvidence-based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.
Qinyuan LiDepartment of Respiratory Medicine, Children's Hospital of Chongqing Medical University, Chongqing, China.
Ling WangSchool of Public Health, Lanzhou University, Lanzhou, China.
Junxian ZhaoSchool of Public Health, Lanzhou University, Lanzhou, China.
Yunlan LiuSchool of Public Health, Lanzhou University, Lanzhou, China.
Renfeng SuSchool of Public Health, Lanzhou University, Lanzhou, China.
Shouyuan WuSchool of Public Health, Lanzhou University, Lanzhou, China.
Xiao LiuSchool of Public Health, Lanzhou University, Lanzhou, China.
Siya ZhaoSchool of Public Health, Lanzhou University, Lanzhou, China.
Qianling ShiThe First School of Clinical Medicine, Lanzhou University, Lanzhou, China.
Janne EstillInstitute of Global Health, University of Geneva, Geneva, Switzerland; Institute of Mathematical Statistics and Actuarial Science, University of Bern, Bern, Switzerland.
Xingrong LiuSchool of Public Health, Lanzhou University, Lanzhou, China. Electronic address: liuxr@lzu.edu.cn.
Wenhong ZhangDepartment of Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, National Medical Center for Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China; National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, China; Key Laboratory of Medical Molecular Virology (MOE/MOH) Shanghai Medical College, Fudan University, Shanghai, China. Electronic address: wenhongzhang@fudan.edu.cn.
Yaolong ChenEvidence-based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China; Lanzhou University Institute of Health Data Science, Lanzhou, China; School of Public Health, Lanzhou University, Lanzhou, China; WHO Collaborating Center for Guideline Implementation and Knowledge Translation, Lanzhou, China; Guideline International Network Asia, Lanzhou, China; Chinese GRADE Center, Lanzhou, China. Electronic address: chevidence@lzu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe the current status of COVID-19 vaccine guidelines. STUDY DESIGN AND

settingWe searched databases, Google and guideline platforms to retrieve COVID-19 vaccine guidelines published between January 1, 2020 and July 8, 2021. We worked in pairs to identify the eligible guidelines and extract data of whether the methodology, funding, and conflict of interests were assessed/reported, and so on. Results were presented descriptively.

resultsA total of 106 COVID-19 vaccine guidelines were included. In the first half of 2021, on average 15 guidelines were published every month. Fifty (47.2%) guidelines addressed the vaccination of people with specific medical conditions, and 18 (17.0%) guidelines focused on adverse effects after vaccination. Only 28 (26.4%) guidelines reported the methodology they used. Four (3.8%) of guidelines assessed both the quality of evidence and strength of recommendations; 42 (39.6%) and 65 (61.3%) guidelines reported their funding sources and conflict of interest, respectively. Most guidelines were published in English (n = 92, 86.8%).

conclusionA high number of guidelines on COVID-19 vaccines have been published in the recent months, but most of them lack clear and transparent reporting of methodology, funding, and conflicts of interest. Rigorous methodological and reporting quality evaluation of these guidelines is needed.

Indexed as

COVID-19COVID-19 VaccinesDatabases, FactualHumansCOVID-19 VaccinesConflict of interestCOVID-19GuidelineMethodologyTransparencyVaccine

Identifiers

PMID34920115
PMCPMC8669940

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.