Evidence map›Paper›PMID 34919767›Full record

ArticleAngewandte Chemie (International ed. in English)2022

Collateral Damage Occurs When Using Photosensitizer Probes to Detect or Modulate Nucleic Acid Modifications.

Aaron M Fleming, Michael B Chabot, Ngoc L B Nguyen, Cynthia J Burrows

Open access · greenAbstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Aaron M FlemingDepartment of Chemistry, University of Utah, 315 S 1400 East, Salt Lake City, Ut84112-0850, USA.
Michael B ChabotDepartment of Chemistry, University of Utah, 315 S 1400 East, Salt Lake City, Ut84112-0850, USA.
Ngoc L B NguyenDepartment of Chemistry, University of Utah, 315 S 1400 East, Salt Lake City, Ut84112-0850, USA.
Cynthia J BurrowsDepartment of Chemistry, University of Utah, 315 S 1400 East, Salt Lake City, Ut84112-0850, USA.ORCID 0000-0001-7253-8529
University of Utah · US

Funding

OXIDATIVE STRESS AND BASE MODIFICATIONS IN REGULATORY DNAR01GM129267 · NIGMS · UNIVERSITY OF UTAH · PI BURROWS, CYNTHIA J · 2018 to 2021
$1.2M
National Science Foundation 1808475NIGMS NIH HHS R01 GM129267NIH HHS R01 GM129267
6 · The paper itself

Abstract

Nucleic acids are chemically modified to fine-tune their properties for biological function. Chemical tools for selective tagging of base modifications enables new approaches; the photosensitizers riboflavin and anthraquinone were previously proposed to oxidize N

Indexed as

DNADNA DamageNucleic Acid ConformationPhotosensitizing AgentsDNAPhotosensitizing Agents5-MethylcytidineGuanosineN6-MethyladenosinePhotooxidationRiboflavin

Identifiers

PMID34919767
PMCPMC8810719
OpenAlexW4200154854

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.