Evidence map›Paper›PMID 34919735›Full record

ArticleJournal of clinical laboratory analysis2022

Detection of folate receptor-positive circulating tumor cells as a biomarker for diagnosis, prognostication, and therapeutic monitoring in breast cancer.

Qian Wu, Hongyun Zheng, Jian Gu, Yanfang Cheng, Bin Qiao, Jingwei Wang, Liang Xiong, Si Sun, Zegang Wu, Anyu Bao and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical laboratory analysis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Folate Receptor Alpha-A Novel Approach to Cancer Therapy.International journal of molecular sciences · 2024
    Review
  6. Nano-inspired smart medicines targeting brain cancer: diagnosis and treatment.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2023
    Review
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Qian WuDepartment of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan, China.ORCID https://orcid.org/0000-0002-7944-2287
Hongyun ZhengDepartment of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan, China.
Jian GuDepartment of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan, China.
Yanfang ChengDepartment of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan, China.
Bin QiaoDepartment of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan, China.
Jingwei WangDepartment of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan, China.
Liang XiongClinical Molecular Diagnostics Institute of Wuhan University, Wuhan, China.
Si SunDepartment of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan, China.
Zegang WuClinical Molecular Diagnostics Institute of Wuhan University, Wuhan, China.
Anyu BaoDepartment of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan, China.
Yongqing TongDepartment of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan, China.
Wuhan University · CN

Funding

Special Novel Coronary Pneumonia Epidemic Prevention and Control Project of Ningxia Hui Autonomous Region 2020BEG01004Special Science and Technology Cooperation Project of Ningxia Hui Autonomous Region Key R&D Program 2018BFG02008Wuhan University College of Medicine Teaching Research Project 2019013
6 · The paper itself

Abstract

objectivesThis study is to explore the clinical significance of folate receptor-positive circulating tumor cells (FR

methodsFolate receptor-positive circulating tumor cells was enriched from peripheral blood of the patients with immunomagnetic separation method and quantitated by folate receptor on the CTC with the ligand-targeted PCR.

resultsThe levels of FR

conclusionsThis study showed the detective rate of FR

Indexed as

Neoplastic Cells, CirculatingAdultBiomarkers, TumorBreast NeoplasmsDisease ProgressionFemaleFolate Receptors, GPI-AnchoredHumansMiddle AgedROC CurveSensitivity and SpecificityBiomarkers, TumorFolate Receptors, GPI-Anchoredbiomarkersbreast cancerdiagnosisfolate receptor-positive circulating tumor cells

Identifiers

PMID34919735
PMCPMC8761444
OpenAlexW4200090945

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.