ArticleThe Gerontologist2022
Establishing a Framework for Gathering Structural and Social Determinants of Health in Alzheimer's Disease Research Centers.
Article in The Gerontologist, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
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Who cites it
50 citing papers in PubMed.
- A world view: Considerations of sociocultural diversity in the study of subjective cognitive decline in Alzheimer's disease and related dementias.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- Orthogonal Contributions of Genetic, Clinical, and Social Determinants of Health Risk Burdens on Alzheimer's Disease Pathophysiology.medRxiv : the preprint server for health sciences · 2026Article
- Abdominal adiposity and Alzheimer's disease imaging markers across sex and race at midlife.Journal of Alzheimer's disease : JAD · 2026Article
- BSO-AD: An Ontology for Representing and Harmonizing Behavioral Social Knowledge in ADRD.medRxiv : the preprint server for health sciences · 2026Article
- Methodological Framework for the Design and Implementation of a US Latine-Hispanic Digital Brain Health Program: User-Centered Design Approach.JMIR formative research · 2026Article
- Diabetes and Hypertension at Midlife Predict Increases in Biomarkers of Dementia Among Black Americans.Journal of racial and ethnic health disparities · 2026Article
- The role of social context in cognitive and neurobehavioural outcomes in epilepsy.Nature reviews. Neurology · 2026Review
- Advancing brain health equity with Indigenous peoples: A critical imperative.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- Recognizing Structural and Social Determinants of Health in the Diagnosis and Care of Dementia.Dementia (London, England) · 2026Article
- Resilience and social support as correlates of dementia risk: insights from a biopsychosocial analysis of the All of Us dataset.Frontiers in public health · 2026Article
- Association Between Structural and Social Determinants of Health and Cognitive Functioning Among African Americans: the ARCHES Cohort.Journal of racial and ethnic health disparities · 2025Article
- Factors associated with age at tau pathology onset and time from tau onset to dementia in Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Interrelationships of Social Determinants with Cognition, Vascular Health, and Physical Functioning.Alzheimer's & dementia. Behavior & socioeconomics of aging · 2025Article
- The impact of tract- and county-level segregation on 10-year cognitive and everyday functioning outcomes of Black/African American older adults in the ACTIVE study.Alzheimer's & dementia. Behavior & socioeconomics of aging · 2025Article
- Revisiting the National Institute on Aging Health Disparities Research Framework: Recommendations for Aging Research.The Gerontologist · 2025Article
- Pathways to Racial/Ethnic Inequalities in Dementia.Annual review of clinical psychology · 2025Review
- Enhancing participation of historically minoritized groups in Alzheimer disease and related dementias research: National Conference Report.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Introducing social determinants of health to the Alzheimer's Disease Research Center network: Development and implementation in the Uniform Data Set.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- The Role of the Neural Exposome as a Novel Strategy to Identify and Mitigate Health Inequities in Alzheimer's Disease and Related Dementias.Molecular neurobiology · 2025Review
- Cumulative Socioeconomic Status Risk is Associated With Greater Increase in Serum Neurofilament Light Chain Levels Among Middle-Aged Black Adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
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Authors and funding
14 authors.
Funding
Abstract
Structural and social determinants of health (SSDoH) are environmental conditions in which individuals are born, live, learn, work, play, worship, and age that affect health, functioning, and quality-of-life outcomes across the life course. Growing evidence suggests that SSDoH can help to explain heterogeneity in outcomes in Alzheimer's disease and Alzheimer's disease and related dementias (AD/ADRD) research and clinical practice. The National Institute on Aging has prioritized collecting SSDoH data to elucidate disease mechanisms and aid discovery of disease-modifying treatments. However, a major nexus of AD/ADRD research, the national network of Alzheimer's Disease Research Centers (ADRCs), collects few SSDoH data. We describe a framework for feasibly gathering and modeling SSDoH data across ADRCs. We lay out key constructs, their measures, and empirical evidence for their importance in elucidating disease and prevention mechanisms. Toward a goal of translation, the framework proposes a modular structure with a core set of measures and options for adjunctive modules. We describe considerations for measuring SSDoH in existing geographically and culturally diverse research cohorts. We also outline a rationale for universal implementation of a set of SSDoH measures and juxtapose the approach with alternatives aimed at collecting SSDoH data.
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