ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2022
Identification of Dementia in Recent Medicare Claims Data, Compared With Rigorous Clinical Assessments.
Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 106 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
106 citing papers in PubMed, 2 syntheses or guidelines pooled it, 107 citations in OpenAlex.
- Case Definition for Diagnosed Alzheimer Disease and Related Dementias in Medicare.JAMA network open · 2024Pooled it
- Ambient air pollution and clinical dementia: systematic review and meta-analysis.BMJ (Clinical research ed.) · 2023Pooled it
- Care Coordination and Hospitalization in Older Adults With or at Risk for Cardiovascular Disease: A Randomized Clinical Trial.JAMA network open · 2026Trial
- Comparative Effectiveness of Two Methods for Assigning Care Coordinators to People Living With Dementia.Journal of the American Geriatrics Society · 2025Trial
- Dementia in Advanced Kidney Disease by Race and Ethnicity and Neighborhood Factors.Kidney international reports · 2026Article
- Identification of prevalent dementia in Medicare Advantage encounters, compared with rigorous cohort assessments.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026Article
- Comparison of Claims-Based Algorithms for Dementia Identification: A Cross-Sectional Analysis of the National Health and Aging Trends Study (NHATS).Journal of the American Geriatrics Society · 2026Article
- Associations of Alzheimer Disease and Related Dementia Neuropathologies With Timely Diagnosis of Dementia in Healthcare Settings.Neurology · 2026Article
- Assigning Probable Dementia Status Using Routinely Collected Electronic Health Record Data.Journal of the American Geriatrics Society · 2026Article
- Trajectories of Medication Use Prior to Death in US Nursing Home Residents With Dementia.Journal of the American Medical Directors Association · 2026Article
- Methodological advances in claims-based dementia algorithms: integrating medication and clinical data for medicare populations.BMC medical research methodology · 2026Article
- Identifying Dual-Eligible Beneficiaries With Long-Term Services and Supports Use in Medicare Enrollment Data.Medical care research and review : MCRR · 2026Article
- Days at Home After Hip Fracture Among Older Adults With and Without Dementia.JAMA network open · 2026Article
- Characterizing treatment initiation with central nervous system-active polypharmacy among adults with dementia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Reduced risk of dementia with recombinant zoster vaccine in US adults age 65 or older.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Detecting multimorbidity patterns in Alzheimer's disease using unsupervised machine learning: A nationwide emergency department study (2007-2022).Journal of Alzheimer's disease : JAD · 2026Article
- Electronic Health Records to Test Multimorbidity Influences to Plasma Biomarker Interpretation for Alzheimer's Disease.Annals of neurology · 2026Article
- A Retrospective National Cohort Study of Trends in Mechanical Ventilation Among Veterans Living With Dementia, 2010-2019.Journal of the American Geriatrics Society · 2026Article
- The association between midlife neighbourhood walkability and Alzheimer's disease in women: a prospective nested case-control study.Age and ageing · 2026Article
- Telehealth among Medicare Advantage beneficiaries with and without Alzheimer's Disease and Related Dementias (ADRD), 2018-2024: from pandemic-era surge to post-pandemic decline.BMC health services research · 2026Observational
46 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundMedicare fee-for-service (FFS) claims data are increasingly leveraged for dementia research. Few studies address the validity of recent claim data to identify dementia, or carefully evaluate characteristics of those assigned the wrong diagnosis in claims.
methodsWe used claims data from 2014 to 2018, linked to participants administered rigorous, annual dementia evaluations in 5 cohorts at the Rush Alzheimer's Disease Center. We compared prevalent dementia diagnosed through the 2016 cohort evaluation versus claims identification of dementia, applying the Bynum-standard algorithm.
resultsOf 1 054 participants with Medicare Parts A and B FFS in a 3-year window surrounding their 2016 index date, 136 had prevalent dementia diagnosed during cohort evaluations; the claims algorithm yielded 217. Sensitivity of claims diagnosis was 79%, specificity 88%, positive predictive value 50%, negative predictive value 97%, and overall accuracy 87%. White participants were disproportionately represented among detected dementia cases (true positive) versus cases missed (false negative) by claims (90% vs 75%, respectively, p = .04). Dementia appeared more severe in detected than missed cases in claims (mean Mini-Mental State Exam = 15.4 vs 22.0, respectively, p < .001; 28% with no limitations in activities of daily living versus 45%, p = .046). By contrast, those with "over-diagnosis" of dementia in claims (false positive) had several worse health indicators than true negatives (eg, self-reported memory concerns = 51% vs 29%, respectively, p < .001; mild cognitive impairment in cohort evaluation = 72% vs 44%, p < .001; mean comorbidities = 7 vs 4, p < .001).
conclusionsRecent Medicare claims perform reasonably well in identifying dementia; however, there are consistent differences in cases of dementia identified through claims than in rigorous cohort evaluations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.