Evidence map›Paper›PMID 34919584›Full record

ArticlePloS one2021

A method for campus-wide SARS-CoV-2 surveillance at a large public university.

Terren Chang, Jolene M Draper, Anouk Van den Bout, Ellen Kephart, Hannah Maul-Newby, Yvonne Vasquez, Jason Woodbury, Savanna Randi, Martina Pedersen, Maeve Nave and 14 more

Abstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Terren ChangColligan Clinical Diagnostic Laboratory, University of California Santa Cruz, Santa Cruz, California, United States of America.
Jolene M DraperColligan Clinical Diagnostic Laboratory, University of California Santa Cruz, Santa Cruz, California, United States of America.
Anouk Van den BoutColligan Clinical Diagnostic Laboratory, University of California Santa Cruz, Santa Cruz, California, United States of America.
Ellen KephartColligan Clinical Diagnostic Laboratory, University of California Santa Cruz, Santa Cruz, California, United States of America.ORCID 0000-0002-3117-4439
Hannah Maul-NewbyColligan Clinical Diagnostic Laboratory, University of California Santa Cruz, Santa Cruz, California, United States of America.
Yvonne VasquezColligan Clinical Diagnostic Laboratory, University of California Santa Cruz, Santa Cruz, California, United States of America.ORCID 0000-0001-6113-5222
Jason WoodburyThirdwave Analytics, San Francisco, California, United States of America.ORCID 0000-0003-4391-7276
Savanna RandiColligan Clinical Diagnostic Laboratory, University of California Santa Cruz, Santa Cruz, California, United States of America.
Martina PedersenColligan Clinical Diagnostic Laboratory, University of California Santa Cruz, Santa Cruz, California, United States of America.
Maeve NaveColligan Clinical Diagnostic Laboratory, University of California Santa Cruz, Santa Cruz, California, United States of America.
Scott LaColligan Clinical Diagnostic Laboratory, University of California Santa Cruz, Santa Cruz, California, United States of America.
Natalie GallagherColligan Clinical Diagnostic Laboratory, University of California Santa Cruz, Santa Cruz, California, United States of America.
Molly M McCabeColligan Clinical Diagnostic Laboratory, University of California Santa Cruz, Santa Cruz, California, United States of America.
Namrita DhillonColligan Clinical Diagnostic Laboratory, University of California Santa Cruz, Santa Cruz, California, United States of America.
Isabel BjorkColligan Clinical Diagnostic Laboratory, University of California Santa Cruz, Santa Cruz, California, United States of America.
Michael LuttrellBusiness and Accounting Services, University of California Santa Cruz, Santa Cruz, California, United States of America.
Frank DangUniversity of California Davis, Davis, California, United States of America.
John B MacMillanColligan Clinical Diagnostic Laboratory, University of California Santa Cruz, Santa Cruz, California, United States of America.
Ralph GreenUniversity of California Davis, Davis, California, United States of America.ORCID 0000-0002-9935-230X
Elizabeth MillerStudent Health Services, University of California Santa Cruz, Santa Cruz, California, United States of America.
Auston M KilpatrickDepartment of Ecology and Evolutionary Biology, University of California Santa Cruz, Santa Cruz, California, United States of America.
Olena VaskeColligan Clinical Diagnostic Laboratory, University of California Santa Cruz, Santa Cruz, California, United States of America.ORCID 0000-0002-1677-417X
Michael D StoneColligan Clinical Diagnostic Laboratory, University of California Santa Cruz, Santa Cruz, California, United States of America.
Jeremy R SanfordColligan Clinical Diagnostic Laboratory, University of California Santa Cruz, Santa Cruz, California, United States of America.ORCID 0000-0002-1131-1627

Funding

Structure and dynamics of the Tetrahymena telomerase ribonucleoproteinR01GM095850 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI STONE, MICHAEL D · 2011 to 2023
$4.4M
Regulation of mRNA FateR35GM130361 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI Jeremy Robert Sanford · 2019 to 2026
$3.1M
Training Program in Molecular, Cell, and Developmental BiologyT32GM133391 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI Needhi Bhalla · 2019 to 2026
$3.0M
NIGMS NIH HHS R01 GM095850NIGMS NIH HHS R35 GM130361NIGMS NIH HHS T32 GM133391
6 · The paper itself

Abstract

The systematic screening of asymptomatic and pre-symptomatic individuals is a powerful tool for controlling community transmission of infectious disease on college campuses. Faced with a paucity of testing in the beginning of the COVID-19 pandemic, many universities developed molecular diagnostic laboratories focused on SARS-CoV-2 diagnostic testing on campus and in their broader communities. We established the UC Santa Cruz Molecular Diagnostic Lab in early April 2020 and began testing clinical samples just five weeks later. Using a clinically-validated laboratory developed test (LDT) that avoided supply chain constraints, an automated sample pooling and processing workflow, and a custom laboratory information management system (LIMS), we expanded testing from a handful of clinical samples per day to thousands per day with the testing capacity to screen our entire campus population twice per week. In this report we describe the technical, logistical, and regulatory processes that enabled our pop-up lab to scale testing and reporting capacity to thousands of tests per day.

Indexed as

Clinical Laboratory TechniquesCOVID-19COVID-19 Nucleic Acid TestingDiagnostic Screening ProgramsDiagnostic Tests, RoutineHumansMass ScreeningPandemicsUniversities

Identifiers

PMID34919584
PMCPMC8682906

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.