Evidence map›Paper›PMID 34919515›Full record

ArticleIEEE transactions on bio-medical engineering2022

Assessment of Calibration Models for Cuff-Less Blood Pressure Measurement After One Year of Aging.

Mohammad Yavarimanesh, Robert C Block, Keerthana Natarajan, Lalit K Mestha, Omer T Inan, Jin-Oh Hahn, Ramakrishna Mukkamala

Open access · greenAbstract read
In one paragraph

Article in IEEE transactions on bio-medical engineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Wearable Photoplethysmography for Cardiovascular Monitoring.Proceedings of the IEEE. Institute of Electrical and Electronics Engineers · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Mohammad Yavarimanesh
Robert C Block
Keerthana Natarajan
Lalit K Mestha
Omer T Inan
Jin-Oh Hahn
Ramakrishna Mukkamala
Michigan State University · USGeorgia Institute of Technology · USThe University of Texas at Austin · USUniversity of Maryland, College Park · USUniversity of Pittsburgh · USUniversity of Rochester · US

Funding

Unobtrusive and Affordable Blood Pressure Monitoring Via Pulse Transit TimeU01EB018818 · NIBIB · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MUKKAMALA, RAMAKRISHNA · 2014 to 2018
$3.4M
A Smartphone-Based Device for Cuff-Less and Calibration-Free Blood Pressure MonitoringR01HL146470 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MUKKAMALA, RAMAKRISHNA · 2019 to 2022
$1.1M
NHLBI NIH HHS R01 HL146470NIBIB NIH HHS U01 EB018818
6 · The paper itself

Abstract

objectiveMany calibration models for cuff-less blood pressure (BP) measurement must be periodically updated with cuff BP values to account for vascular aging. However, the time period required for these "cuff re-calibrations" is largely unknown. The impact of one year of aging on several calibration models was assessed.

methodsTen humans (6 males, 57±18 years, 3 hypertensives) were studied during multiple recording sessions that occurred one year apart. In each session, electrocardiography (ECG), ear photoplethysmography (PPG), finger PPG, and toe PPG waveforms and manual cuff BP were recorded before and after slow breathing, mental arithmetic, cold pressor, and nitroglycerin. Linear models based on each PPG waveform, which were previously shown to offer value in predicting the intervention-induced BP changes in a larger subject cohort, were employed. The model coefficients were determined for each subject via one session, and the fully-defined, subject-specific calibration models were then evaluated in the corresponding subjects via the session one year later.

resultsOnly a linear model relating toe pulse arrival time (PAT) - time delay between ECG R-wave and toe PPG foot - to systolic BP (SBP) remained useful. After the year, this model changed little on average (root-mean-squared-error (RMSE) = 1.5 mmHg) and predicted the cuff BP values better than the average of the initial cuff BP values of the subject (RMSE = 9.6±0.8 mmHg vs. 12.7±1.0 mmHg; p < 0.05).

conclusionThese results suggest annual cuff recalibrations for the toe PAT-SBP model. SIGNIFICANCE: Toe PAT may offer a practical recalibration period that fosters user adherence.

Indexed as

Blood Pressure DeterminationPulse Wave AnalysisAgingBlood PressureCalibrationHumansMalePhotoplethysmography

Identifiers

PMID34919515
PMCPMC9154072
OpenAlexW4200070088

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.