Evidence map›Paper›PMID 34918948›Full record

Observational studyCannabis and cannabinoid research2023

Observed Impact of Long-Term Consumption of Oral Cannabidiol on Liver Function in Healthy Adults.

Robert Kaufmann, Keith Aqua, Jeff Lombardo, Martin Lee

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in Cannabis and cannabinoid research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. The Role of Cannabidiol in Liver Disease: A Systemic Review.International journal of molecular sciences · 2024
    Pooled it
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  3. Effects of a cannabidiol/terpene formulation on sleep in individuals with insomnia: a double-blind, placebo-controlled, randomized, crossover study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Robert KaufmannMidwest Allergy Sinus Asthma PC, Springfield, Illinois, USA.ORCID 0000-0001-5964-6840
Keith AquaSyzygy Research Solutions, LLC, Wellington, Florida, USA.ORCID 0000-0003-2986-5262
Jeff LombardoUniversity of Buffalo, Buffalo, New York, USA.ORCID 0000-0002-4750-4447
Martin LeeUCLA Fielding School of Public Health, Los Angeles, California, USA.ORCID 0000-0002-8421-7295
Asthma Association · BGClinical Research Solutions · USUniversity at Buffalo, State University of New York · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CannabidiolAdultAlkaline PhosphataseBilirubinFemaleHumansInfantLiverLiver Function TestsMaleAlkaline PhosphataseBilirubinCannabidiolALTASTcannabidiolCBDliver function testLT

Identifiers

PMID34918948
PMCPMC9940803
OpenAlexW4200595139

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.