ArticleThe Journal of clinical investigation1987
Interleukin 1 induces cultured human endothelial cell production of granulocyte-macrophage colony-stimulating factor.
Article in The Journal of clinical investigation, 1987. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 204 citations in OpenAlex.
- The Molecular and Genetic Mechanisms of Inherited Bone Marrow Failure Syndromes: The Role of Inflammatory Cytokines in Their Pathogenesis.Biomolecules · 2023Review
- Review
- Diversity of Vascular Niches in Bones and Joints During Homeostasis, Ageing, and Diseases.Frontiers in immunology · 2021Review
- Bone Angiogenesis and Vascular Niche Remodeling in Stress, Aging, and Diseases.Frontiers in cell and developmental biology · 2020Review
- Inflammatory bone marrow microenvironment.Hematology. American Society of Hematology. Education Program · 2019Review
- Impact of inflammation on early hematopoiesis and the microenvironment.International journal of hematology · 2017Review
- Inflamm-Aging of Hematopoiesis, Hematopoietic Stem Cells, and the Bone Marrow Microenvironment.Frontiers in immunology · 2016Review
- Exogenous endothelial cells as accelerators of hematopoietic reconstitution.Journal of translational medicine · 2012Review
- Tumor necrosis factor-alpha and endothelial cells modulate Notch signaling in the bone marrow microenvironment during inflammation.Experimental hematology · 2008Article
- Article
- Article
- Granulocyte macrophage colony stimulating factor produced in lesioned peripheral nerves induces the up-regulation of cell surface expression of MAC-2 by macrophages and Schwann cells.The Journal of cell biology · 1996Article
- Adhesion-independent synergy of monocytes and endothelial cells in cytokine production: regulation of IL-6 and GM-CSF production by PAF.Mediators of inflammation · 1996Article
- Molecular regulation of the human IL-3 gene: inducible T cell-restricted expression requires intact AP-1 and Elf-1 nuclear protein binding sites.The Journal of experimental medicine · 1993Article
- Evidence that granulocyte macrophage-colony-stimulating factor regulates the distribution and differentiated state of dendritic cells/Langerhans cells in human lung and lung cancers.The Journal of clinical investigation · 1993Article
- Eosinophil hematopoietins antagonize the programmed cell death of eosinophils. Cytokine and glucocorticoid effects on eosinophils maintained by endothelial cell-conditioned medium.The Journal of clinical investigation · 1991Article
- The potential role of recombinant hematopoietic colony-stimulating factors in preventing infections in the immunocompromised host.The Canadian journal of infectious diseases = Journal canadien des maladies infectieuses · 1991Article
- LPS-stimulated bovine aortic endothelial cells produce IL-1 and IL-6 like activities.Agents and actions · 1990Article
- Granulocyte-macrophage colony-stimulating factor promotes differentiation and survival of human peripheral blood dendritic cells in vitro.The Journal of clinical investigation · 1990Article
- The Jeremiah Metzger lecture. Regulation of hematopoiesis.Transactions of the American Clinical and Climatological Association · 1990Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Monokine-stimulated endothelial cells are known to produce both burst- and colony-stimulating activities, but neither the nature of the monokine nor the hematopoietic growth factor(s) produced is known. We show by mRNA analysis that an immortalized line of human endothelial cells constitutively produce granulocyte-macrophage colony-stimulating factor. Furthermore, interleukin 1 and tumor necrosis factor induce early passage human umbilical endothelial cells to produce the same growth factor.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.