Evidence map›Paper›PMID 34918299›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2022

Establishment of In Vivo Ovarian Cancer Mouse Models Using Intraperitoneal Tumor Cell Injection.

Sonam Mittal, Prachi Gupta, Pradeep Chaluvally-Raghavan, Sunila Pradeep

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sonam MittalDepartment of Obstetrics and Gynecology, Medical College of Wisconsin, Milwaukee, WI, USA.
Prachi GuptaDepartment of Obstetrics and Gynecology, Medical College of Wisconsin, Milwaukee, WI, USA.
Pradeep Chaluvally-RaghavanDepartment of Obstetrics and Gynecology, Medical College of Wisconsin, Milwaukee, WI, USA.
Sunila PradeepDepartment of Obstetrics and Gynecology, Medical College of Wisconsin, Milwaukee, WI, USA. spradeep@mcw.edu.
Medical College of Wisconsin · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mouse models-xenograft models, syngeneic models (directly implanted or chemically or virally induced), and genetically engineered mice (including transgenic and knockout methods) are invaluable for preclinical studies of ovarian cancer as they recapitulate the structures and microenvironments of tumors, which in vitro studies are unable to accomplish.This chapter describes the methodology and approaches for generating various murine models currently employed in ovarian cancer research. It covers the implantation of cells from ovarian cancer cell lines into mice by intraperitoneal injection.

Indexed as

Ovarian NeoplasmsAnimalsCarcinoma, Ovarian EpithelialCell Line, TumorDisease Models, AnimalFemaleInjections, IntraperitonealMiceTumor MicroenvironmentIn vivo modelsOvarian cancerSyngeneic modelsXenograft models

Identifiers

PMID34918299
OpenAlexW4200082450

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.