Evidence map›Paper›PMID 34918295›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2022

Isolation of Fallopian Tube Epithelium for Assessment of Cilia Beating Frequency (CBF).

Angela Russo, Joanna E Burdette

Open access · greenAbstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
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  6. Article
  7. A new look at the theoretical causes of endometriosis: Narrative review.International journal of reproductive biomedicine · 2024
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Angela RussoDepartment of Pharmaceutical Sciences and Center for Biomolecular Sciences, University of Illinois at Chicago, Chicago, IL, USA. russoa@uic.edu.
Joanna E BurdetteDepartment of Pharmaceutical Sciences and Center for Biomolecular Sciences, University of Illinois at Chicago, Chicago, IL, USA.
University of Illinois Chicago · US

Funding

Tumor Environment and Metastasis (TEAM) Research ProgramP30CA060553 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LEONIDAS C. PLATANIAS · 1993 to 2026
$153.9M
Microfluidic Models of Ovarian Cancer Preneoplastic LesionsR01CA240301 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Joanna E Burdette, Jonathan Coppeta · 2019 to 2026
$4.6M
PCOS and androgen-related disease modeling and drug testing in Multi-organ Integrated Microfluidic Reproductive PlatformUH3ES029073 · NIEHS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KIM, JI-YONG JULIE · 2019 to 2021
$3.6M
Imaging mass spectrometry methodologies for studying the metabolites of cancer metastasisR01CA240423 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI BURDETTE, JOANNA E, SANCHEZ, LAURA MARGARET · 2020 to 2024
$2.1M
NCI NIH HHS P30 CA060553NCI NIH HHS R01 CA240301NCI NIH HHS R01 CA240423NIEHS NIH HHS UH3 ES029073
6 · The paper itself

Abstract

The fallopian tube epithelium (FTE) plays a critical role in reproduction and the genesis of ovarian cancer. The FTE columnar cells present with hair-like structures named "cilia" that are required for normal FTE function. Impairment of ciliary motion can lead to infertility, and it is influenced by hormonal signaling and endocrine disrupting compounds. Studying how cilia beating changes in response to these compounds is critical for understanding FTE physiology and pathology. In this protocol, we describe methods for isolating human fallopian tube epithelium, oviduct (murine equivalent of fallopian tube) epithelium, and ovaries. In addition, we describe methods for imaging and measuring cilia beating frequency using high-resolution time-lapse imaging.

Indexed as

CiliaEpitheliumFallopian TubesAnimalsFemaleHumansMiceOvaryReproductionCilia beating frequencyFallopian tube epitheliumOvaryOviductOvulation

Identifiers

PMID34918295
PMCPMC9088221
OpenAlexW4200459919

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.