Evidence map›Paper›PMID 34918091›Full record

ArticleJournal of the National Cancer Institute2022

Association of Health-Care System and Survival in African American and Non-Hispanic White Patients With Bladder Cancer.

Nikhil V Kotha, Abhishek Kumar, Edmund M Qiao, Alex S Qian, Rohith S Voora, Vinit Nalawade, A Karim Kader, Rana R McKay, Tyler F Stewart, Brent S Rose

Open access · greenAbstract read
In one paragraph

Article in Journal of the National Cancer Institute, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Nikhil V KothaSchool of Medicine, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0001-9737-5033
Abhishek KumarVeterans Affairs San Diego Healthcare System, San Diego, CA, USA.ORCID 0000-0002-2306-8863
Edmund M QiaoSchool of Medicine, University of California San Diego, La Jolla, CA, USA.
Alex S QianSchool of Medicine, University of California San Diego, La Jolla, CA, USA.
Rohith S VooraSchool of Medicine, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0001-9242-844X
Vinit NalawadeVeterans Affairs San Diego Healthcare System, San Diego, CA, USA.ORCID 0000-0002-6594-6740
A Karim KaderDepartment of Urology, University of California San Diego, La Jolla, CA, USA.
Rana R McKayDivision of Hematology-Oncology, Department of Medicine, University of California San Diego, La Jolla, CA, USA.
Tyler F StewartDivision of Hematology-Oncology, Department of Medicine, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0002-8170-264X
Brent S RoseVeterans Affairs San Diego Healthcare System, San Diego, CA, USA.
University of California San Diego · US

Funding

VIRAL MALIGNANCYP30CA023100 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jesse Nodora · 1985 to 2026
$124.9M
NCI NIH HHS P30 CA023100
6 · The paper itself

Abstract

backgroundAfrican American patients with bladder cancer have inferior outcomes compared with non-Hispanic White (White) patients. We hypothesize that access to health care is a primary determinant of this disparity. We compared outcomes by race for patients with bladder cancer receiving care within the predominant hybrid-payer health-care model of the United States captured in the Surveillance, Epidemiology, and End Results (SEER) database with those receiving care within the equal-access model of the Veterans' Health Administration (VHA).

methodsAfrican American and White patients diagnosed with bladder cancer were identified in SEER and VHA. Stage at presentation, bladder cancer-specific mortality (BCM), and overall survival (OS) were compared by race within each health-care system.

resultsThe SEER cohort included 122 449 patients (93.7% White, 6.3% African American). The VHA cohort included 36 322 patients (91.0% White, 9.0% African American). In both cohorts, African American patients were more likely to present with muscle-invasive disease and metastases, but the differences between races were statistically significantly smaller in VHA. In SEER multivariable models, African American patients had worse BCM (hazard ratio [HR] = 1.22, 95% confidence interval [CI] = 1.15 to 1.29) and OS (HR = 1.26, 95% CI = 1.20 to 1.31). In contrast within the VHA, African American patients had similar BCM (HR = 0.97, 95% CI = 0.88 to 1.07) and OS (HR = 0.99, 95% CI = 0.93 to 1.05).

conclusionsIn this study of contrasting health-care models, receiving medical care in an equal-access system was associated with reduced differences in stage at presentation and eliminated disparities in survival outcomes for African American patients with bladder cancer. Our findings highlight the importance of reducing financial barriers to care to notably improve health equity and oncologic outcomes for African American patients.

Indexed as

Black or African AmericanUrinary Bladder NeoplasmsDelivery of Health CareHumansRare DiseasesSEER ProgramUnited StatesUnited States Department of Veterans AffairsWhite People

Identifiers

PMID34918091
PMCPMC9002275
OpenAlexW4200467510

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.