Evidence map›Paper›PMID 34917994›Full record

ReviewCurrent research in microbial sciences2022

A review on association of fungi with the development and progression of carcinogenesis in the human body.

Marie Andrea Laetitia Huët, Chuen Zhang Lee, Sadequr Rahman

Open access · goldAbstract readReview
In one paragraph

Review in Current research in microbial sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.4field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Esophageal cancer: from pathogenesis to precision therapies.Signal transduction and targeted therapy · 2026
    Review
  3. Mycobiome: an underexplored kingdom in cancer.Microbiology and molecular biology reviews : MMBR · 2025
    Review
  4. Review
  5. Review
  6. Biomedicines · 2025
    Review
  7. Review
  8. Article
  9. Alginate Extracted fromPolymers · 2024
    Article
  10. Article
  11. Review
  12. Non-self glycan structures as possible modulators of cancer progression: would polysaccharides from Cryptococcus spp. impact this phenomenon?Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
    Review
  13. A Putative Role ofMicroorganisms · 2023
    Review
  14. Review
  15. Article
  16. What IsMicroorganisms · 2022
    Review
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Marie Andrea Laetitia HuëtSchool of Science, Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway,Subang Jaya, Selangor 47500, Malaysia.
Chuen Zhang LeeSchool of Science, Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway,Subang Jaya, Selangor 47500, Malaysia.
Sadequr RahmanSchool of Science, Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway,Subang Jaya, Selangor 47500, Malaysia.
Monash University Malaysia · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role and impact of commensal and pathogenic fungi in different parts of the human body are being increasingly appreciated, unveiling the importance of such microorganisms in human health. A key function is the involvement of the mycobiota in cross-kingdom interactions within the microbiome. Any disturbance in the functionality of the microbiota could alter metabolic reactions, have a negative impact on homeostasis or induce diseases. The association of fungi with cancer development is the focus of this review. Several studies have reported direct or indirect involvement of fungal pathogens and mycobiome dysbiosis in induction of carcinogenesis. Most studies focused on cancers of the gastrointestinal tract. However, researchers are now investigating other organs, such as the skin, where the significant results obtained confirm the involvement of fungal pathogens and administration of antifungal drugs in development of cancer. This review gives an overview of the different organs affected and describes the mechanisms used by these eukaryotes or antifungals to induce oncogenesis.

Indexed as

CancerFungal dysbiosisFungal pathogenHuman mycobiotaMetastasis

Identifiers

PMID34917994
PMCPMC8666644
OpenAlexW4200114190

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.