Evidence map›Paper›PMID 34917985›Full record

ArticleHGG advances2022

Identification of a common polymorphism in

Benjamin J Landis, Dongbing Lai, Dong-Chuan Guo, Joel S Corvera, Muhammad T Idrees, Henry W Stadler, Christian Cuevas, Gavin U Needler, Courtney E Vujakovich, Dianna M Milewicz and 2 more

Open access · goldAbstract read
In one paragraph

Article in HGG advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Benjamin J LandisDepartment of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, 46202, United States of America.
Dongbing LaiDepartment of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, 46202, United States of America.
Dong-Chuan GuoDepartment of Internal Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, 77030, United States of America.
Joel S CorveraDepartment of Surgery, Indiana University School of Medicine, Indianapolis, IN, 46202, United States of America.
Muhammad T IdreesDepartment of Pathology, Indiana University School of Medicine, Indianapolis, IN, 46202, United States of America.
Henry W StadlerDepartment of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, 46202, United States of America.
Christian CuevasDepartment of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, 46202, United States of America.
Gavin U NeedlerDepartment of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, 46202, United States of America.
Courtney E VujakovichDepartment of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, 46202, United States of America.
Dianna M MilewiczDepartment of Internal Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, 77030, United States of America.
Robert B HintonDivison of Cardiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, United States of America.
Stephanie M WareDepartment of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, 46202, United States of America.
Indiana University School of MedicineThe University of Texas Health Science Center · USCincinnati Children's Hospital Medical Center · US

Funding

Genetic Predisposition To Thoracic Aortic Aneurysms/DissectionsR01HL109942 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MILEWICZ, DIANNA M · 2012 to 2023
$7.5M
Indiana Pediatric Scientist Award(IPSA)K12HD068371 · NICHD · INDIANA UNIVERSITY INDIANAPOLIS · PI CLAPP, DAVID W · 2013 to 2017
$1.9M
Investigating the role of mitochondria in thoracic aortic aneurysm pathogenesisK23HL141667 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI LANDIS, BENJAMIN JOHN · 2019 to 2023
$810k
NHLBI NIH HHS K23 HL141667NHLBI NIH HHS R01 HL109942NICHD NIH HHS K12 HD068371
6 · The paper itself

Abstract

Thoracic aortic aneurysm (TAA) predisposes to sudden, life-threatening aortic dissection. The factors that regulate interindividual variability in TAA severity are not well understood. Identifying a molecular basis for this variability has the potential to improve clinical risk stratification and advance mechanistic insight. We previously identified

Identifiers

PMID34917985
PMCPMC8670066
OpenAlexW3201400590

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.