Tracking neuronal motility in live murine retinal explants.

Nozie D Aghaizu, Katherine M Warre-Cornish, Martha R Robinson, Robin R Ali, Rachael A Pearson

Open access · goldAbstract read

In one paragraph

Article in STAR protocols, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.1field-weighted citation impact, top 54% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

Retinal Explant Culture from Mouse, Human, and Nonhuman Primates and Its Applications in Vision Research.Methods in molecular biology (Clifton, N.J.) · 2025
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nozie D AghaizuUniversity College London, Institute of Ophthalmology, London EC1V 9EL, UK.

Katherine M Warre-CornishUniversity College London, Institute of Ophthalmology, London EC1V 9EL, UK.

Martha R RobinsonUniversity College London, Institute of Ophthalmology, London EC1V 9EL, UK.

Robin R AliUniversity College London, Institute of Ophthalmology, London EC1V 9EL, UK.

Rachael A PearsonUniversity College London, Institute of Ophthalmology, London EC1V 9EL, UK.

University College London · GB

Funding

Medical Research Council MR/J004553/1Medical Research Council MR/T002735/1Medical Research Council MR/T002735/2

6 · The paper itself

Abstract

The developing retina undergoes dynamic organizational changes involving significant intra-retinal motility of the encompassing cells. Here, we present a protocol for tracking retinal cell motility in live explanted mouse retinae. Although originally applied to rod and cone photoreceptors, this strategy is applicable to any fluorescently labeled cell in mouse retinae and other similar experimental retinal models. Careful tissue handling is critical for the successful acquisition of high-quality live imaging data. Further instructions for semi-automated

Indexed as

RetinaRetinal Cone Photoreceptor CellsRetinal Rod Photoreceptor CellsAnimalsCell MovementCell TrackingFemaleLuminescent ProteinsMaleMiceMice, TransgenicMicroscopy, FluorescenceTime-Lapse ImagingLuminescent ProteinsCell BiologyDevelopmental biologyMicroscopyModel OrganismsNeuroscience

Identifiers

PMID34917982

DOI10.1016/j.xpro.2021.101008

PMCPMC8666713

OpenAlexW4200038656

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.