Evidence map›Paper›PMID 34917972›Full record

ArticleSTAR protocols2021

Differentiation of human pluripotent stem cells into pancreatic duct-like organoids.

Markus Breunig, Jessica Merkle, Michael Karl Melzer, Sandra Heller, Thomas Seufferlein, Matthias Meier, Meike Hohwieler, Alexander Kleger

Abstract read
In one paragraph

Article in STAR protocols, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Markus BreunigDepartment of Internal Medicine I, Ulm University Hospital, 89081 Ulm, Germany.
Jessica MerkleDepartment of Internal Medicine I, Ulm University Hospital, 89081 Ulm, Germany.
Michael Karl MelzerDepartment of Internal Medicine I, Ulm University Hospital, 89081 Ulm, Germany.
Sandra HellerDepartment of Internal Medicine I, Ulm University Hospital, 89081 Ulm, Germany.
Thomas SeufferleinDepartment of Internal Medicine I, Ulm University Hospital, 89081 Ulm, Germany.
Matthias MeierHelmholtz Pioneer Campus, Helmholtz Zentrum München, 85764 München, Germany.
Meike HohwielerDepartment of Internal Medicine I, Ulm University Hospital, 89081 Ulm, Germany.
Alexander KlegerDepartment of Internal Medicine I, Ulm University Hospital, 89081 Ulm, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recapitulation of human developmental processes and pathological manifestations requires access to specific cell types and precursor stages during embryogenesis and disease. Here, we describe a scalable

Indexed as

Cell Culture TechniquesCell DifferentiationCell LineHumansOrganoidsPancreatic DuctsPluripotent Stem CellsCell cultureCell DifferentiationDevelopmental biologyOrganoidsStem Cells

Identifiers

PMID34917972
PMCPMC8669107

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.