ArticlePhysics and imaging in radiation oncology2021
Combining inter-observer variability, range and setup uncertainty in a variance-based sensitivity analysis for proton therapy.
Article in Physics and imaging in radiation oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 8 citations in OpenAlex.
- Upright positioning enhances beam angle optimization and organ sparing in head and neck carbon-ion radiotherapy with fixed-beam systems.Radiation oncology (London, England) · 2025Article
- A review of the clinical introduction of 4D particle therapy research concepts.Physics and imaging in radiation oncology · 2024Review
- Surveying the clinical practice of treatment adaptation and motion management in particle therapy.Physics and imaging in radiation oncology · 2023Article
- Interobserver Variability Prediction of Primary Gross Tumor in a Patient with Non-Small Cell Lung Cancer.Cancers · 2022Article
- Five years, 20 volumes and 300 publications ofPhysics and imaging in radiation oncology · 2022Article
- Towards an integral clinical proton dose prediction uncertainty by considering delineation variation.Physics and imaging in radiation oncology · 2022Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Margin concepts in proton therapy aim to ensure full dose coverage of the clinical target volume (CTV) in presence of setup and range uncertainty. Due to inter-observer variability (IOV), the CTV itself is uncertain. We present a framework to evaluate the combined impact of IOV, setup and range uncertainty in a variance-based sensitivity analysis (SA). For ten patients with skull base meningioma, the mean calculation time to perform the SA including 1.6 × 10
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