ArticleFrontiers in medicine2021
A First in Human Trial Implanting Microalgae Shows Safety of Photosynthetic Therapy for the Effective Treatment of Full Thickness Skin Wounds.
Article in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03960164 (Safety Use of Photosynthetic Dermal Scaffolds for the Treatment of Acute Wounds), which is not on this map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Safety Use of Photosynthetic Dermal Scaffolds for the Treatment of Acute Wounds
Who cites it
23 citing papers in PubMed, 58 citations in OpenAlex.
- Oxygen Supply of Islets of Langerhans by Photosynthetically Active Microalgae in Bioprinted Co-Cultures Maintains Their Function in a Hypoxic Environment.Advanced healthcare materials · 2026Article
- Microalgae as a Novel Therapy for Chronic Wound Healing.International wound journal · 2026Review
- Cell- and biological-based drug delivery vectors for cancer treatment.Frontiers in molecular biosciences · 2026Review
- Oxygen-releasing scaffolds in tissue engineering: design strategies, fabrication and regenerative applications.Regenerative biomaterials · 2026Review
- A breath of fresh air: the role of oxygen carriers in plastic surgery.Frontiers in bioengineering and biotechnology · 2026Review
- Microalgae: emerging forces and prospects in the field of wound healing.Burns & trauma · 2026Review
- Photosynthetic Solutions for Organ Perfusion Based on Microalgae and Cyanobacteria Display DifferentialACS applied bio materials · 2025Article
- Effect of recombinant protein production and release on microalgal fitness and the impact of environmental conditions for localized therapeutic delivery.Journal of biological engineering · 2025Article
- Therapeutic potential of microalgae-derived natural compounds in diabetic wound healing: A comprehensive review.Heliyon · 2025Review
- Microalgae and Human Disorders: Mechanistic Insights and Therapeutic Potential.Current topics in medicinal chemistry · 2025Review
- Towards chlorocytes for therapeutic intravascular photosynthesis.Applied microbiology and biotechnology · 2024Review
- Dual roles of photosynthetic hydrogel with sustained oxygen generation in promoting cell survival and eradicating anaerobic infection.Materials today. Bio · 2024Article
- Biomedical engineering utilizing living photosynthetic cyanobacteria and microalgae: Current status and future prospects.Materials today. Bio · 2024Review
- Calcium alginate elastic capsules for microalgal cultivation.RSC advances · 2024Article
- The effect of continuous long-term illumination with visible light in different spectral ranges on mammalian cells.Scientific reports · 2024Article
- The microalgaMaterials today. Bio · 2024Article
- Hypoxic environment of wounds and photosynthesis-based oxygen therapy.Burns & trauma · 2024Review
- Development of a new kappa-carrageenan hydrogel system to study benthic diatom vertical movements.PloS one · 2024Article
- The development of live microorganism-based oxygen shuttles for enhanced hypoxic tumor therapy.Materials today. Bio · 2023Review
- Development of an implantable three-dimensional model of a functional pathogenic multispecies biofilm to study infected wounds.Scientific reports · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Insufficient oxygen supply represents a relevant issue in several fields of human physiology and medicine. It has been suggested that the implantation of photosynthetic cells can provide oxygen to tissues in the absence of a vascular supply. This approach has been demonstrated to be successful in several
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.