Evidence map›Paper›PMID 34917566›Full record

ReviewFrontiers in pediatrics2021

Cellular Origin(s) of Congenital Diaphragmatic Hernia.

Gabriëla G Edel, Gerben Schaaf, Rene M H Wijnen, Dick Tibboel, Gabrielle Kardon, Robbert J Rottier

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Gabriëla G EdelDepartment of Pediatric Surgery and Intensive Care, Erasmus MC-Sophia Children's Hospital, Rotterdam, Netherlands.
Gerben SchaafDepartment of Clinical Genetics, Erasmus MC, Rotterdam, Netherlands.
Rene M H WijnenDepartment of Pediatric Surgery and Intensive Care, Erasmus MC-Sophia Children's Hospital, Rotterdam, Netherlands.
Dick TibboelDepartment of Pediatric Surgery and Intensive Care, Erasmus MC-Sophia Children's Hospital, Rotterdam, Netherlands.
Gabrielle KardonDepartment of Human Genetics, University of Utah, Salt Lake City, UT, United States.
Robbert J RottierDepartment of Pediatric Surgery and Intensive Care, Erasmus MC-Sophia Children's Hospital, Rotterdam, Netherlands.
Erasmus MC · NLErasmus MC - Sophia Children’s Hospital · NLErasmus University Rotterdam · NLUniversity of Utah · US

Funding

Genetic and Environmental Regulation of Diaphragm Development and Congenital Diaphragmatic HerniasR01HD104317 · NICHD · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI KARDON, GABRIELLE · 2021 to 2025
$2.4M
NICHD NIH HHS R01 HD104317
6 · The paper itself

Abstract

Congenital diaphragmatic hernia (CDH) is a structural birth defect characterized by a diaphragmatic defect, lung hypoplasia and structural vascular defects. In spite of recent developments, the pathogenesis of CDH is still poorly understood. CDH is a complex congenital disorder with multifactorial etiology consisting of genetic, cellular and mechanical factors. This review explores the cellular origin of CDH pathogenesis in the diaphragm and lungs and describes recent developments in basic and translational CDH research.

Indexed as

congenital diaphragmatic hernia (CDH)diaphragmmesotheliumperivascular cellspleuroperitoneal folds

Identifiers

PMID34917566
PMCPMC8669812
OpenAlexW3215978811

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.