Evidence map›Paper›PMID 34917408›Full record

ArticleSouthern African journal of HIV medicine2021

Evaluation of an SMS-based mHealth intervention to enhance early infant diagnosis follow-up testing and assessment of postnatal prophylaxis.

Anele Dube-Pule, Brian C Zanoni, Cathy Connolly, Majahonkhe Shabangu, Moherndran Archary

Open access · goldAbstract read
In one paragraph

Article in Southern African journal of HIV medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Anele Dube-PuleDepartment of Paediatrics and Child Health, Faculty of Medicine, University of KwaZulu-Natal, Durban, South Africa.ORCID https://orcid.org/0000-0003-4833-4360
Brian C ZanoniDepartment of Pediatrics, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, United States of America.ORCID https://orcid.org/0000-0002-8640-7703
Cathy ConnollySchool of Public Health, University of KwaZulu-Natal, Durban, South Africa.ORCID https://orcid.org/0000-0002-3506-4915
Majahonkhe ShabanguSawubona Health Inc., Malden, Massachusetts, United States of America.ORCID https://orcid.org/0000-0002-6794-8096
Moherndran ArcharyDepartment of Paediatrics and Child Health, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.ORCID https://orcid.org/0000-0003-3082-9234
University of KwaZulu-Natal · ZAEmory University · USKing Edward VIII Hospital · ZAUniversity of Cape Town · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdherence to infant antiretroviral (ARV) postnatal prophylaxis and early infant diagnosis (EID) uptake is low in Africa. Promoting EID and adherence are necessary for this age group.

objectivesWe evaluated an SMS-based mobile health (mHealth) intervention to enhance adherence to ARV prophylaxis and knowledge of EID and prevention of mother-to-child transmission (PMTCT) among high-risk and low-risk mother-infant pairs.

methodTwo hundred and fifty-one mothers were recruited from King Edward VIII Hospital between December 2018 and October 2019. Participant information was captured, and SMS reminders were sent postnatally to promote immunisation attendance. Follow-up HIV polymerase chain reaction (PCR) test results were reviewed, and telephonic interviews were utilised for qualitative data.

resultsIn all, 73.3% of infants had HIV PCR tests performed at 10 weeks. This high rate could be attributed to the mHealth intervention as this is considerably higher than other national studies, though not statistically significant compared to rates reported in the district at the same time. Factors that have impacted follow-up EID rates include poor maternal knowledge of EID time points and inadequate implementation of national PMTCT protocols. High-risk mothers were younger, commenced antenatal clinic visit later, were less knowledgeable on prophylaxis and have lower-birthweight infants than lower-risk mothers.

conclusionmHealth can play an important role in improving EID by increasing maternal knowledge. Further studies should focus on whether maternal education over an mHealth platform can increase knowledge on PMTCT and subsequently increase EID.

Indexed as

early infant diagnosishigh-risk mothersHIV DNA PCRinfant prophylaxislow-risk mothersmHealthPMTCTSMS reminders

Identifiers

PMID34917408
PMCPMC8661286
OpenAlexW3214991247

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.