Evidence map›Paper›PMID 34917315›Full record

ArticleFrontline gastroenterology2021

Implementation of a care bundle improves the management of patients with non-alcoholic fatty liver disease.

Laura Jane Neilson, Louise Macdougall, Phey Shen Lee, Timothy Hardy, David Beaton, Subashini Chandrapalan, Alaa Ebraheem, Mohammed Hussien, Sarah Galbraith, Shi Looi and 10 more

Open access · hybridAbstract read
In one paragraph

Article in Frontline gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Measuring NAFLD models of care.Nature reviews. Gastroenterology & hepatology · 2023
    Article
  6. Article
  7. Article
  8. Screening strategy for non-alcoholic fatty liver disease.Clinical and molecular hepatology · 2023
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Gastroenterology 2022: Groundhog Day.Frontline gastroenterology · 2022
    Article
  14. Advancing the global public health agenda for NAFLD: a consensus statement.Nature reviews. Gastroenterology & hepatology · 2022
    Review
  15. Defining comprehensive models of care for NAFLD.Nature reviews. Gastroenterology & hepatology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 6 institutions in 1 country.

Laura Jane NeilsonLiver Unit, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK.ORCID 0000-0002-7185-0825
Louise MacdougallLiver Unit, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK.
Phey Shen LeeLiver Unit, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK.ORCID 0000-0002-6007-8227
Timothy HardyLiver Unit, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK.
David BeatonDepartment of Gastroenterology, University Hospital of North Tees, Stockton-on-Tees, UK.
Subashini ChandrapalanDepartment of Gastroenterology, University Hospital of North Durham, Durham, UK.ORCID 0000-0002-1582-3224
Alaa EbraheemDepartment of Gastroenterology, Gateshead Health NHS Foundation Trust, Gateshead, UK.
Mohammed HussienDepartment of Gastroenterology, Gateshead Health NHS Foundation Trust, Gateshead, UK.
Sarah GalbraithDepartment of Gastroenterology, Northumbria Healthcare NHS Foundation Trust, North Shields, UK.
Shi LooiDepartment of Gastroenterology, University Hospital of North Durham, Durham, UK.
Sophia OxenburghDepartment of Gastroenterology, University Hospital of North Tees, Stockton-on-Tees, UK.
Naw April PhawLiver Unit, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK.
William TaylorDepartment of Gastroenterology, Darlington Memorial Hospital, Darlington, UK.
Laura HaighLiver Unit, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK.
Kate HallsworthLiver Unit, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK.
Dina MansourDepartment of Gastroenterology, Gateshead Health NHS Foundation Trust, Gateshead, UK.
Jessica K DysonLiver Unit, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK.
Steven MassonLiver Unit, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK.
Quentin AnsteeLiver Unit, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK.
Stuart McPhersonLiver Unit, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK.
Newcastle upon Tyne Hospitals NHS Foundation Trust · GBGateshead Health NHS Foundation Trust · GBUniversity Hospital of North Durham · GBUniversity Hospital of North Tees · GBDarlington Memorial Hospital · GBNorthumbria Healthcare NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNon-alcoholic fatty liver disease (NAFLD) is common and is associated with liver-related and cardiovascular-related morbidity. Our aims were: (1) to review the current management of patients with NAFLD attending hospital clinics in North East England (NEE) and assess the variability in care; (2) develop a NAFLD 'care bundle' to standardise care; (3) to assess the impact of implementation of the NAFLD care bundle.

methodsA retrospective review was conducted to determine baseline management of patients with NAFLD attending seven hospitals in NEE. A care bundle for the management of NAFLD was developed including important recommendations from international guidelines. Impact of implementation of the bundle was evaluated prospectively in a single centre.

resultsBaseline management was assessed in 147 patients attending gastroenterology, hepatology and a specialist NAFLD clinic. Overall, there was significant variability in the lifestyle advice given and management of metabolic risk factors, with patients attending an NAFLD clinic significantly more likely to achieve >10% body weight loss and have metabolic risk factors addressed. Following introduction of the NAFLD bundle 50 patients were evaluated. Use of the bundle was associated with significantly better documentation and implementation of most aspects of patient management including management of metabolic risk factors, documented lifestyle advice and provision of NAFLD-specific patient advice booklets.

conclusionThe introduction of an outpatient 'care bundle' led to significant improvements in the assessment and management of patients with NAFLD in the NEE and could help improve and standardise care if used more widely.

Indexed as

fatty livernonalcoholic steatohepatitis

Identifiers

PMID34917315
PMCPMC8640379
OpenAlexW3118638934

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.