Evidence map›Paper›PMID 34917262›Full record

ArticleOncotarget2021

Radiomics in predicting recurrence for patients with locally advanced breast cancer using quantitative ultrasound.

Archya Dasgupta, Divya Bhardwaj, Daniel DiCenzo, Kashuf Fatima, Laurentius Oscar Osapoetra, Karina Quiaoit, Murtuza Saifuddin, Stephen Brade, Maureen Trudeau, Sonal Gandhi and 8 more

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 1 country.

Archya DasguptaDepartment of Radiation Oncology, Sunnybrook Health Sciences Centre, Toronto, Canada.
Divya BhardwajPhysical Sciences, Sunnybrook Research Institute, Toronto, Canada.
Daniel DiCenzoPhysical Sciences, Sunnybrook Research Institute, Toronto, Canada.
Kashuf FatimaPhysical Sciences, Sunnybrook Research Institute, Toronto, Canada.
Laurentius Oscar OsapoetraPhysical Sciences, Sunnybrook Research Institute, Toronto, Canada.
Karina QuiaoitPhysical Sciences, Sunnybrook Research Institute, Toronto, Canada.
Murtuza SaifuddinPhysical Sciences, Sunnybrook Research Institute, Toronto, Canada.
Stephen BradePhysical Sciences, Sunnybrook Research Institute, Toronto, Canada.
Maureen TrudeauDepartment of Medical Oncology, Department of Medicine, Sunnybrook Health Sciences Centre, Toronto, Canada.
Sonal GandhiDepartment of Medical Oncology, Department of Medicine, Sunnybrook Health Sciences Centre, Toronto, Canada.
Andrea EisenDepartment of Medical Oncology, Department of Medicine, Sunnybrook Health Sciences Centre, Toronto, Canada.
Frances WrightDepartment of Surgical Oncology, Department of Surgery, Sunnybrook Health Sciences Centre, Toronto, Canada.
Nicole Look-HongDepartment of Surgical Oncology, Department of Surgery, Sunnybrook Health Sciences Centre, Toronto, Canada.
Ali Sadeghi-NainiDepartment of Radiation Oncology, Sunnybrook Health Sciences Centre, Toronto, Canada.
Belinda CurpenDepartment of Medical Imaging, Sunnybrook Health Sciences Centre, Toronto, Canada.
Michael C KoliosDepartment of Physics, Ryerson University, Toronto, Canada.
Lakshmanan SannachiPhysical Sciences, Sunnybrook Research Institute, Toronto, Canada.
Gregory J CzarnotaDepartment of Radiation Oncology, Sunnybrook Health Sciences Centre, Toronto, Canada.
Sunnybrook Health Science Centre · CAHealth Sciences Centre · CASunnybrook Research InstituteUniversity of Toronto · CAToronto Metropolitan University · CAYork University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe purpose of the study was to investigate the role of pre-treatment quantitative ultrasound (QUS)-radiomics in predicting recurrence for patients with locally advanced breast cancer (LABC). MATERIALS AND

methodsA prospective study was conducted in patients with LABC (

resultsWith a median follow up of 69 months (range 7-118 months), 28 patients had disease recurrence (local or distant). The best classification results were obtained using an SVM classifier with a sensitivity, specificity, accuracy and area under curve of 71%, 87%, 82%, and 0.76, respectively. Using the SVM model for the predicted non-recurrence and recurrence groups, the estimated 5-year recurrence-free survival was 83% and 54% (

conclusionsA QUS-radiomics model using higher-order texture derivatives can identify patients with LABC at higher risk of disease recurrence before starting treatment.

Indexed as

breast cancermachine learningquantitative ultrasoundradiomicsrecurrence

Identifiers

PMID34917262
PMCPMC8664392
OpenAlexW4200214032

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.