Evidence map›Paper›PMID 34917183›Full record

ArticleExperimental and therapeutic medicine2022

Impact of modern personalized treatment of breast cancer on surgical attitude and outcomes.

Ciprian Tănăsescu, Dragos Serban, Andrei Moisin, Carmen Popa, Ramona Coca, George Iancu, Mihail Silviu Tudosie, Daniel Ovidiu Costea, Bogdan Socea, Corneliu Tudor and 3 more

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Ciprian TănăsescuSurgical Clinical Department, Faculty of Medicine, 'Lucian Blaga' University, 550169 Sibiu, Romania.
Dragos SerbanDepartment of General Surgery, Faculty of Medicine, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Andrei MoisinDepartment of Surgery, Sibiu County Clinical Emergency Hospital, 550245 Sibiu, Romania.
Carmen PopaDepartment of Surgery, Sibiu County Clinical Emergency Hospital, 550245 Sibiu, Romania.
Ramona CocaSurgical Clinical Department, Faculty of Medicine, 'Lucian Blaga' University, 550169 Sibiu, Romania.
George IancuDepartment of Obstetrics and Gynecology, 'Filantropia' Clinical Hospital, 011132 Bucharest, Romania.
Mihail Silviu TudosieDepartment of Clinical Toxicology, Faculty Of Medicine, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Daniel Ovidiu CosteaDepartment of Clinical Surgical Disciplines I, Faculty of Medicine, 'Ovidius' University, 900470 Constanta, Romania.
Bogdan SoceaDepartment of General Surgery, Faculty of Medicine, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Corneliu TudorIVth Department of Surgery, Emergency University Hospital, 050098 Bucharest, Romania.
Gabriel Andrei GanguraDepartment of General Surgery, Faculty of Medicine, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Laura Carina TribusDepartment of Internal Medicine Gastroenterology, Faculty of Medicine, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Gabriel Catalin SmarandacheDepartment of General Surgery, Faculty of Medicine, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Carol Davila University of Medicine and Pharmacy · ROClinical Emergency Hospital Bucharest · ROLucian Blaga University of Sibiu · ROOvidius University · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multimodal treatment of breast cancer has made steady progress in recent years. The involvement of modern oncology, diagnostic imaging techniques and surgical treatment, have brought a definite benefit to patients, defining the multidisciplinary treatment of breast cancer. The introduction of immunohistochemical testing and genetic screening has led to the prioritization of therapy according to their results and a correct approach to initiating treatment. The main aim of the present study was to conduct a comparative analysis through a retrospective study of the therapeutic means used in breast cancer with the statistical evaluation of the obtained results. To carry out the study, a group of 125 patients hospitalized during the period January 2015 to December 2020, were included, and the parameters were selected from the observation sheets. The results of the study demonstrated the superiority of multimodal treatment of breast cancer over surgical treatment as the only therapeutic management. The introduction of ultrasound-guided biopsies and conservative surgical options has led to increased diagnostic accuracy and a significant improvement in aesthetic outcome. The multidisciplinary approach to breast cancer allows an individualized treatment by performing immunohistochemical testing and through the use of neoadjuvant and adjuvant treatment combined with conservative surgical techniques with a more favorable cosmetic and oncological result, with reduced postoperative complications.

Indexed as

breast cancerimmunohistochemical analysismultimodal therapyneoadjuvant chemotherapyoutcomessurgery

Identifiers

PMID34917183
PMCPMC8630438
OpenAlexW3212928094

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.