Evidence map›Paper›PMID 34917074›Full record

ArticleFrontiers in immunology2021

Secretome Profiling of Atlantic Salmon Head Kidney Leukocytes Highlights the Role of Phagocytes in the Immune Response to Soluble β-Glucan.

Dimitar B Iliev, Guro Strandskog, Mehrdad Sobhkhez, Jack A Bruun, Jorunn B Jørgensen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Dimitar B IlievThe Norwegian College of Fishery Science, UiT The Arctic University of Norway, Tromsø, Norway.
Guro StrandskogThe Norwegian College of Fishery Science, UiT The Arctic University of Norway, Tromsø, Norway.
Mehrdad SobhkhezThe Norwegian College of Fishery Science, UiT The Arctic University of Norway, Tromsø, Norway.
Jack A BruunDepartment of Medical Biology, Proteomics Platform, UiT The Arctic University of Norway, Tromsø, Norway.
Jorunn B JørgensenThe Norwegian College of Fishery Science, UiT The Arctic University of Norway, Tromsø, Norway.
UiT The Arctic University of Norway · NOInstitute of Molecular Biology · BG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

β-Glucans (BG) are glucose polymers which are produced in bacteria and fungi but not in vertebrate organisms. Being recognized by phagocytic leukocytes including macrophages and neutrophils through receptors such as dectin-1 and Complement receptor 3 (CR3), the BG are perceived by the innate immune system of vertebrates as foreign substances known as Pathogen Associated Molecular Patterns (PAMPs). The yeast-derived BG has been recognized for its potent biological activity and it is used as an immunomodulator in human and veterinary medicine. The goal of the current study was to characterize the immunostimulatory activity of soluble yeast BG in primary cultures of Atlantic salmon (

Indexed as

Animalsbeta-GlucansExtracellular VesiclesGene Expression ProfilingHead KidneyImmunity, InnateLeukocytesPhagocytesSalmo salarSecretomebeta-GlucansAtlantic salmonexosomesextracellular vesiclesleukocytesmononuclear phagocytespolymorphonuclear granulocytesβ‐Glucan

Identifiers

PMID34917074
PMCPMC8671040
OpenAlexW3215312066

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.