Evidence map›Paper›PMID 34916927›Full record

ArticleFrontiers in aging neuroscience2021

The Neutrophil to Lymphocyte Ratio Is Associated With the Risk of Subsequent Dementia in the Framingham Heart Study.

Jaime Ramos-Cejudo, Andrew D Johnson, Alexa Beiser, Sudha Seshadri, Joel Salinas, Jeffrey S Berger, Nathanael R Fillmore, Nhan Do, Chunlei Zheng, Zanetta Kovbasyuk and 7 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 47 citations in OpenAlex.

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  6. Neutrophil-to-Lymphocyte Ratio in the Alzheimer's Disease Continuum.International journal of molecular sciences · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 9 institutions in 1 country.

Jaime Ramos-CejudoDepartment of Psychiatry, New York University Grossman School of Medicine, New York, NY, United States.
Andrew D JohnsonPopulation Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, Framingham, MA, United States.
Alexa BeiserThe Framingham Heart Study, Boston, MA, United States.
Sudha SeshadriThe Framingham Heart Study, Boston, MA, United States.
Joel SalinasThe Framingham Heart Study, Boston, MA, United States.
Jeffrey S BergerDivision of Vascular Surgery, Department of Surgery, NYU Grossman School of Medicine, New York, NY, United States.
Nathanael R FillmoreVA Boston Cooperative Studies Program, MAVERIC, VA Boston Healthcare System, Boston, MA, United States.
Nhan DoVA Boston Cooperative Studies Program, MAVERIC, VA Boston Healthcare System, Boston, MA, United States.
Chunlei ZhengVA Boston Cooperative Studies Program, MAVERIC, VA Boston Healthcare System, Boston, MA, United States.
Zanetta KovbasyukDepartment of Psychiatry, New York University Grossman School of Medicine, New York, NY, United States.
Babak A ArdekaniDepartment of Psychiatry, New York University Grossman School of Medicine, New York, NY, United States.
Omonigho M BubuDepartment of Psychiatry, New York University Grossman School of Medicine, New York, NY, United States.
Ankit ParekhDivision of Pulmonary, Critical Care and Sleep Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Antonio ConvitDepartment of Psychiatry, New York University Grossman School of Medicine, New York, NY, United States.
Rebecca A BetenskyDepartment of Biostatistics, New York University School of Global Public Health, New York, NY, United States.
Thomas M WisniewskiDepartment of Psychiatry, New York University Grossman School of Medicine, New York, NY, United States.
Ricardo S OsorioDepartment of Psychiatry, New York University Grossman School of Medicine, New York, NY, United States.
New York University · USBoston University · USNathan Kline Institute for Psychiatric Research · USCenter for Neuro-Oncology · USFramingham Heart Study · USHarvard University · USIcahn School of Medicine at Mount Sinai · USNational Heart Lung and Blood Institute · USVA Boston Healthcare System · US

Funding

Research Education ComponentP30AG066512 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Mary Sherman Mittelman · 2020 to 2026
$28.4M
Transgenic/Behavior CoreP01AG060882 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI UEBERHEIDE, BEATRIX MAGDALENA · 2020 to 2024
$12.0M
The mediating role of Slow Wave Sleep and Vascular Risk Factors on Alzheimer Disease related disparity between African-Americans and non-Hispanic WhitesK23AG068534 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BUBU, OMONIGHO A MICHAEL · 2021 to 2025
$958k
Quantitative Social Phenotyping in Alzheimer's DiseaseK23AG057760 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SALINAS, JOEL ARMANDO · 2018 to 2022
$788k
Sustained Attention Neuroimaging in Sleep ApneaK25HL151912 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI PAREKH, ANKIT ASHOK · 2021 to 2025
$775k
NHLBI NIH HHS K25 HL151912NIA NIH HHS K23 AG057760NIA NIH HHS K23 AG068534NIA NIH HHS L30 AG064670NIA NIH HHS P01 AG060882NIA NIH HHS P30 AG066512NINDS NIH HHS L30 NS093525
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alzheimer’s diseasecomplete blood count (CBC)dementiaFHSFraminghamneutrophil to lymphocyte ratioNLRrisk prediction

Identifiers

PMID34916927
PMCPMC8670436
OpenAlexW3217076079

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.