SynthesisFrontiers in human neuroscience2021
Cortical Activation During Finger Tapping Task Performance in Parkinson's Disease Is Influenced by Priming Conditions: An ALE Meta-Analysis.
Synthesis in Frontiers in human neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Leader and Follower Roles in Adapted Tango Reveal Complementary Neural Routes to Motor Improvement in Parkinson's Disease.medRxiv : the preprint server for health sciences · 2026Article
- Auditory cueing modulates motor performance and brain activity in early Parkinson's disease-a kinematic and fMRI study.NPJ Parkinson's disease · 2026Article
- Motor cortex stimulation ameliorates parkinsonian locomotor deficits: effectual and mechanistic differences from subthalamic modulation.NPJ Parkinson's disease · 2025Article
- Neural mechanisms underlying synchronization of movement to musical cues in Parkinson disease and aging.Frontiers in neuroscience · 2025Article
- Preserved auditory-motor synchronization during finger-tapping to music and metronomes at various tempi in progressive multiple sclerosis.Frontiers in neurology · 2025Article
- Early cortico-muscular coherence and cortical network changes in Parkinson's patients treated with MRgFUS.Frontiers in neurology · 2024Article
- UPSIT subitems may predict motor progression in Parkinson's disease.Frontiers in neurology · 2023Article
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Authors and funding
6 authors.
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Abstract
The finger tapping task (FTT) is commonly used in the evaluation of dyskinesia among patients with Parkinson's disease (PD). Past research has indicated that cortical activation during FTT is different between self-priming and cue-priming conditions. To evaluate how priming conditions affect the distribution of brain activation and the reorganization of brain function, and to investigate the differences in brain activation areas during FTT between PD patients and healthy control (HC) participants, we conducted an activation likelihood estimation (ALE) meta-analysis on the existing literature. Analyses were based on data from 15 independent samples that included 181 participants with PD and 164 HC participants. We found that there was significantly more activation in the middle frontal gyrus, precentral gyrus, post-central gyrus, superior parietal lobe, inferior parietal lobule, cerebellum, and basal ganglia during FTT in PD patients than in HCs. In self-priming conditions, PD patients had less activation in the parietal lobe and insular cortex but more activation in the cerebellum than the HCs. In cue-priming conditions, the PD patients showed less activation in the cerebellum and frontal-parietal areas and more activation in the superior frontal gyrus and superior temporal gyrus than the HCs. Our study illustrates that cue-priming manipulations affect the distribution of activity in brain regions involved in motor control and motor performance in PD patients. In cue-priming conditions, brain activity in regions associated with perceptual processing and inhibitory control was enhanced, while sensory motor areas associated with attention and motor control were impaired.
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