ArticleHIV/AIDS (Auckland, N.Z.)2021
Mother-to-Child Transmission of HIV and Associated Factors Among Exposed Infants in Pastoralist Health Facilities, South Omo Zone, Ethiopia, 2020 - A Retrospective Cross-Sectional Study.
Article in HIV/AIDS (Auckland, N.Z.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- Magnitude and risk factors of mother-to-child transmission of HIV among HIV-exposed infants after Option B+ implementation in Ethiopia: a systematic review and meta-analysis.AIDS research and therapy · 2024Pooled it
- Pooled it
- Factors associated with HIV infection among infants born to mothers with HIV in Blantyre, Malawi: a mixed methods study.BMC public health · 2026Article
- Maternal and infant predictors of early mother-to-child transmission among HIV-exposed infants in the Karamoja region, Northeastern Uganda 2020-2023, a retrospective cross-sectional study.BMC infectious diseases · 2026Article
- Frequency of HIV Infection Among Pregnant Women in a Tertiary Care Hospital in Islamabad, Pakistan.Cureus · 2025Article
- Low effective coverage of HIV testing and counselling services during antenatal care in Ethiopia: evidence from the demographic and health survey and service provision assessment.BMJ public health · 2024Article
- Determinants of HIV infection at 18 months of age among HIV-exposed infants in the context of PMTCT interventions in southern Ethiopia.Frontiers in reproductive health · 2024Article
- Effect of Dolutegravir-Based First-Line Antiretroviral Therapy on Mother-to-Child Transmission of HIV Among HIV-Exposed Infants in Ethiopia: a Before-and-After Study.HIV/AIDS (Auckland, N.Z.) · 2024Article
- Incidence of HIV Infection among HIV-Exposed Iinfants at Gondar University Hospital from 2019-2021: A Prospective Cohort Study.Ethiopian journal of health sciences · 2023Article
- Seroepidemiology of HBV, HCV, HIV, HTLV, and CMV in Pregnant Women Referring to Sari Birth Cohort.Advanced biomedical research · 2022Article
- Prevalence of HIV infection and associated factors among infants born to HIV-positive mothers in health institutions, northwest Ethiopia, 2021.Women's health (London, England)Article
- HIV Sero-status Outcomes and Associated Factors Among HIV-Exposed Children at Four Public Hospitals in Addis Ababa, Ethiopia (2018-2023): A Cross-Sectional Study.Journal of the International Association of Providers of AIDS CareArticle
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3 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough HIV/AIDS is affecting all age groups, it is a primary cause of illness and deaths among children globally. A significant bulk of HIV infections in children under the age of 15 were as a result of vertical transmission, where it accounts for 95% of childhood HIV infections in Ethiopia.
objectiveTo assess the proportion of mother-to-child transmission (MTCT) of HIV and associated factors among exposed infants on follow-up in pastoralist health facilities, South Omo, Ethiopia. METHODOLOGY: A retrospective, cross-sectional study was employed among 228 HIV-exposed infants. Medical records of HIV-exposed infant-mother pairs in the study institutions were extracted. The confirmatory HIV serostatus of every infant was taken at the end of 24 months. Data were entered in Epi Data 4.2 version and exported to SPSS version 25 for final analysis. Multivariable logistic regression analysis was used to identify significant predictor variables at P-value < 0.05.
resultsA total of 228 records were included in the analysis. The rate of HIV transmission was 5.3% (95% CI: 2.6-8.3%). Not receiving antiretroviral prophylaxis at birth (AOR = 5.8, 95% CI: 1.02-33.53), absence of maternal antiretroviral prior to current pregnancy (AOR = 5.6, 95% CI: 1.14-28.1), and mother's advanced World Health Organization clinical stage of HIV (AOR: 10.5, 95% CI: 1.4-81) were associated with MTCT of HIV.
conclusionThis study identified a high proportion of MTCT among exposed infants in the study area. Not receiving antiretrovirals prior to pregnancy and advanced WHO clinical stage of HIV, and not getting antiretroviral prophylaxis at birth resulted in higher risk of MTCT of HIV. Hence, health workers and policy-makers should offer antiretroviral prophylaxis, put mothers on antiretroviral therapy and limit the stage of HIV at lower WHO clinical stages.
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