Evidence map›Paper›PMID 34916803›Full record

ArticleMicrobiology insights2021

Antimicrobial Resistance in

Saroj Khadka, Basudha Shrestha, Anil Pokhrel, Sachin Khadka, Rajesh Dhoj Joshi, Megha Raj Banjara

Open access · goldAbstract read
In one paragraph

Article in Microbiology insights, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Antimicrobial Resistance Patterns and Prevalence ofInterdisciplinary perspectives on infectious diseases · 2025
    Article
  4. Observational
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Saroj KhadkaCentral Department of Microbiology, Tribhuvan University, Kirtipur, Nepal.ORCID https://orcid.org/0000-0001-7533-7933
Basudha ShresthaDepartment of Microbiology, Kathmandu Model Hospital, Kathmandu, Nepal.
Anil PokhrelCentral Department of Microbiology, Tribhuvan University, Kirtipur, Nepal.ORCID https://orcid.org/0000-0002-1903-0387
Sachin KhadkaDepartment of Medicine, Kathmandu Model Hospital, Kathmandu, Nepal.
Rajesh Dhoj JoshiDepartment of Medicine, Kathmandu Model Hospital, Kathmandu, Nepal.
Megha Raj BanjaraCentral Department of Microbiology, Tribhuvan University, Kirtipur, Nepal.ORCID https://orcid.org/0000-0002-5024-6127
Tribhuvan University · NPKathmandu Medical College Teaching Hospital · NP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe morbidity and mortality due to typhoid fever can be significantly reduced with the use of effective antibiotics. At present, fluoroquinolones, third generation cephalosporins, and azithromycin are widely used to treat typhoid fever. However, changing antibiotic susceptibility among PATIENTS AND

methodsA total of 706 blood specimens were collected from febrile patients attending the outpatient department of Kathmandu Model Hospital during June to September, 2018. The antibiotic susceptibility testing for 11 different antibiotics (nalidixic acid, ciprofloxacin, ofloxacin, levofloxacin, cefixime, ceftriaxone, cefotaxime, azithromycin, cotrimoxazole, chloramphenicol, and amoxicillin) was performed by disk diffusion method. Furthermore, minimum inhibitory concentration (MIC) values of ciprofloxacin, ofloxacin, and azithromycin were determined by agar dilution method. Mutation at

resultsOut of 706 blood samples, 6.94% (n = 49) were culture positive for

conclusionFluoroquinolones have poor activity against

Indexed as

antibiotic resistanceazithromycinFluoroquinoloneminimum inhibitory concentrationSalmonellatyphoid fever

Identifiers

PMID34916803
PMCPMC8669115
OpenAlexW4200046622

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.