ArticleIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine2021
Therapeutic Plasma Exchange in Pediatric Intensive Care Unit: A Single-center Experience.
Article in Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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6 citing papers in PubMed, 12 citations in OpenAlex.
- Therapeutic Plasma Exchange in Pediatric Care: Insights from a Tertiary Care Centre Experience.Indian pediatrics · 2026Article
- Key technical aspects and vascular access safety in membrane-based therapeutic plasma exchange for the pediatric population.Archives of medical science : AMS · 2026Article
- Eculizumab as first-line treatment for patients with severe presentation of complement factor H antibody-mediated hemolytic uremic syndrome.Pediatric nephrology (Berlin, Germany) · 2025Article
- Therapeutic Plasma Exchange in Pediatric Intensive Care and Brief Overview of the Literature.Sisli Etfal Hastanesi tip bulteni · 2025Article
- Prevalence of extracorporeal blood purification techniques in critically ill patients before and during the COVID-19 pandemic in Egypt.Acute and critical care · 2024Article
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3 authors at 1 institution in 1 country.
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Abstract
AIM AND
objectiveTo examine the clinical characteristics, indications, and complications of patients undergoing therapeutic plasma exchange (TPE) in our pediatric intensive care unit (PICU). MATERIALS AND
methodsPatients who underwent therapeutic plasma exchange between January 2018 and January 2020 in the PICU were included in the study. Demographic, clinical, and laboratory data of patients were obtained retrospectively from medical records. A venous catheter was placed into subclavian, femoral, or jugular veins. The number of plasmapheresis sessions for each patient was determined by observing the course of the disease and clinical improvement. Patients were monitored for vital signs during the plasmapheresis process. Complications directly associated with TPE were recorded.
resultsDuring the 2-year study period, 105 TPE sessions were performed in 25 patients (15 males/10 females). The median age was 84 months (6-204), and the median body weight was 32 kg (8-75). Renal disorders and sepsis were the most common group, and about 48% of patients were in these groups. The most common diagnoses were sepsis with multi-organ dysfunction syndrome in seven patients and followed by hemolytic uremic syndrome (five patients) and Guillain-Barre syndrome (three patients). Nausea (6.7%) and hypocalcemia (6.7%) were the most common complications of patients associated with the procedure. Premature discontinuation of the procedure were not seen due to complications. Complications were treated with symptomatic therapy.
conclusionTPE is an effective treatment that can be safely used for pediatric patients with developments in PICUs. Nevertheless, TPE should be performed by experienced staff at a specialized center to minimize the risk of complications. HOW TO CITE THIS ARTICLE: Özsoylu S, Dursun A,
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