ArticleEuropean journal of human genetics : EJHG2022
The use of polygenic risk scores in pre-implantation genetic testing: an unproven, unethical practice.
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Article in European journal of human genetics : EJHG, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 46 papers.
0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed.
- Public perceptions of polygenic testing and embryo selection for non-medical traits.Nature human behaviour · 2026Article
- Decision-making criteria in polygenic embryo screening: A survey of reproductive medicine physicians.Genetics in medicine : official journal of the American College of Medical Genetics · 2026Article
- An introduction to polygenic scores - methodological basics and recent advances.Medizinische Genetik : Mitteilungsblatt des Berufsverbandes Medizinische Genetik e.V · 2026Article
- Patient Perspectives on Psychiatric Polygenic Risk Scores in Reproductive Decision-Making and Polygenic Embryo Screening.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2026Article
- Polygenic risk scores in clinical applications - opportunities and challenges.Medizinische Genetik : Mitteilungsblatt des Berufsverbandes Medizinische Genetik e.V · 2026Article
- Modeling polygenic embryo screening in real-world IVF patients demonstrates limitations on efficacy.medRxiv : the preprint server for health sciences · 2026Article
- Governance of polygenic embryo screening: a qualitative study on the perspectives of clinicians and patients.Fertility and sterility · 2026Article
- Polygenic risk scores: Navigating the future of precision medicine through economic, ethical, and scientific advancements.iScience · 2026Review
- Ethical and social implications of implementing polygenic embryo screening into clinical care: A scoping review.Genetics in medicine open · 2026Review
- The new frontier in assisted reproduction : Consumer Desire vs. Regulatory and Ethical Precaution in AI-assisted Polygenic Embryo Screening.EMBO reports · 2026Article
- Survey of U.S. reproductive medicine clinicians' attitudes on polygenic embryo screening.NPJ genomic medicine · 2025Article
- Singaporean attitudes to cognitive enhancement: a cross-sectional survey.Journal of medical ethics · 2025Article
- Polygenic risk scores and embryonic screening: considerations for regulation.Journal of medical ethics · 2025Article
- Article
- Consent and its discontents: the case of UK Biobank.Medicine, health care, and philosophy · 2025Article
- Social and Behavioral Genomics: On the Ethics of the Research and Its Downstream Applications.Annual review of genomics and human genetics · 2025Review
- Risk factors and prediction for pediatric obesity: current status and future perspectives.Endocrine journal · 2025Review
- Promises and pitfalls of preimplantation genetic testing for polygenic disorders: a narrative review.F&S reviews · 2025Article
- Foretelling the Future: Preimplantation Genetic Testing and the Coming of Polygenic Embryo Screening.Journal of clinical medicine · 2025Review
- Population-based genetic carrier screening. A consensus statement from the Spanish societies: AEGH, AEDP, ASEBIR, SEAGEN, SEF and SEGCD.European journal of human genetics : EJHG · 2025Review
Corrections and comments
- Commented on by
- Erratum issued
- Erratum issued
Authors and funding
16 authors.
Francesca ForzanoClinical Genetics Department, Guy's and St Thomas NHS Foundation Trust, London, UK. francesca.forzano@nhs.net.ORCID http://orcid.org/0000-0001-5632-0052
Olga AntonovaDepartment of Medical Genetics, Medical University of Sofia, Sofia, Bulgaria.ORCID http://orcid.org/0000-0003-3123-4830
Angus ClarkeDivision of Cancer and Genetics, School of Medicine, Cardiff University, Cardiff, Wales, UK.ORCID http://orcid.org/0000-0002-1200-9286
Guido de WertMaastricht University, Maastricht, The Netherlands.ORCID http://orcid.org/0000-0002-0410-4902
Sabine HentzeHuman Genetics, Heidelberg, Germany.
Yalda JamshidiGenetics Research Centre, Molecular and Clinical Sciences Institute, St George's University of London, London, UK.ORCID http://orcid.org/0000-0003-0151-6482
Yves MoreauUniversity of Leuven ESAT-STADIUS, B-3001, Leuven, Belgium.
Markus PerolaFinnish Institute for Health and Welfare (THL), Biomedicum 1, Haartmaninkatu 8, 00290, Helsinki, Finland.
Inga ProkopenkoDepartment of Clinical & Experimental Medicine, University of Surrey, Guildford, UK.
Andrew ReadCentre for Genomic Medicine, St Mary's Hospital, Manchester, M13 0JH, England.
Alexandre ReymondCenter for Integrative Genomics, University of Lausanne, CH-1015, Lausanne, Switzerland.ORCID http://orcid.org/0000-0003-1030-8327
Vigdis StefansdottirDepartment of Genetics and Molecular Medicine, Landspitali University Hospital, Reykjavik, Iceland.ORCID http://orcid.org/0000-0003-4451-3126
Carla van ElSection Community Genetics, Department of Clinical Genetics and Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0003-2201-2320
Maurizio GenuardiUOC Genetica Medica, Dipartimento di Scienze di Laboratorio e Infettivologiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.ORCID http://orcid.org/0000-0002-7410-8351
Executive Committee of the European Society of Human Genetics
Public and Professional Policy Committee of the European Society of Human Genetics
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Genome-Wide Association StudyMultifactorial InheritanceGenetic Predisposition to DiseaseGenetic TestingHumansRisk Factors
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.