Evidence map›Paper›PMID 34916576›Full record

ArticleScientific reports2021

Predicting the individual probability of macular hole closure following intravitreal ocriplasmin injections for vitreomacular traction release using baseline characteristics.

Thomas Bertelmann, Lars Berndzen, Thomas Raber, Sebastian Pfeiffer, Andreas Leha, Christoph Paul, Nicolas Feltgen, Sebastian Bemme

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Thomas BertelmannDepartment of Ophthalmology, University Medical Center Goettingen, Robert-Koch-Straße 40, 37075, Goettingen, Germany. thomas.bertelmann@med.uni-goettingen.de.
Lars BerndzenDepartment of Ophthalmology, University Medical Center Goettingen, Robert-Koch-Straße 40, 37075, Goettingen, Germany.
Thomas RaberOxurion NV, Leuven, Belgium.
Sebastian PfeifferUMG Study Center, University Medical Center Goettingen, Goettingen, Germany.
Andreas LehaDepartment of Medical Biometry and Statistical Bioinformatics, University Medical Center Goettingen, Goettingen, Germany.
Christoph PaulDepartment of Ophthalmology, Philipps-University Marburg, Marburg, Germany.
Nicolas FeltgenDepartment of Ophthalmology, University Medical Center Goettingen, Robert-Koch-Straße 40, 37075, Goettingen, Germany.
Sebastian BemmeDepartment of Ophthalmology, University Medical Center Goettingen, Robert-Koch-Straße 40, 37075, Goettingen, Germany.
University of Göttingen · DEOxurion (Belgium) · BEPhilipps University of Marburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The primary objective was to create and establish a new formula that predicts the individual probability of macular hole closure for eyes with full thickness macular holes (FTMH) accompanied by vitreomacular traction (VMT) which received enzymatic vitreolysis using intravitreally administered ocriplasmin. The secondary objective was to evaluate the forecast reliability of a previously published formula for VMT resolution in VMT-only eyes (Odds

Indexed as

AgedAged, 80 and overFemaleFibrinolysinForecastingHumansIntravitreal InjectionsMaleMiddle AgedPeptide FragmentsProbabilityRetinal PerforationsRetrospective StudiesTreatment OutcomeVitrectomyVitreous DetachmentFibrinolysinmicroplasminPeptide Fragments

Identifiers

PMID34916576
PMCPMC8677762
OpenAlexW4200598483

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.