Evidence map›Paper›PMID 34916436›Full record

ArticleNeural regeneration research2022

Hypothermia selectively protects the anterior forebrain mesocircuit during global cerebral ischemia.

Xiao-Hua Wang, Wei Jiang, Si-Yuan Zhang, Bin-Bin Nie, Yi Zheng, Feng Yan, Jian-Feng Lei, Tian-Long Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neural regeneration research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Xiao-Hua WangDepartment of Anesthesiology, Xuanwu Hospital, Capital Medical University; National Clinical Research Center for Geriatric Disorders, Beijing, China.
Wei JiangDepartment of Anesthesiology, Third Medical Center of People's Liberation Army General Hospital, Beijing, China.
Si-Yuan ZhangDaxing Hospital Affiliated to Capital Medical University, Beijing, China.
Bin-Bin NieBeijing Engineering Research Center of Radiographic Techniques and Equipment, Institute of High Energy Physics, Chinese Academy of Sciences; School of Nuclear Science and Technology, University of Chinese Academy of Sciences, Beijing, China.
Yi ZhengNeuroprotection Research Laboratory, Departments of Radiology and Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA.
Feng YanCerebrovascular Research Center, Xuanwu Hospital, Capital Medical University, Beijing, China.
Jian-Feng LeiCerebrovascular Research Center, Xuanwu Hospital, Capital Medical University, Beijing, China.
Tian-Long WangDepartment of Anesthesiology, Xuanwu Hospital, Capital Medical University; National Clinical Research Center for Geriatric Disorders, Beijing, China.
Capital Medical University · CNNational Clinical Research Center for Digestive Diseases · CNInstitute of High Energy Physics · CNMassachusetts General Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypothermia is an important protective strategy against global cerebral ischemia following cardiac arrest. However, the mechanisms of hypothermia underlying the changes in different regions and connections of the brain have not been fully elucidated. This study aims to identify the metabolic nodes and connection integrity of specific brain regions in rats with global cerebral ischemia that are most affected by hypothermia treatment.

Indexed as

anterior forebrain mesocircuitcardiac arrestcorpus callosumglobal cerebral ischemiahypometabolic areashypothermiamagnetic resonance imagingpositron emission tomographyprefrontal cortexratsthalamus

Identifiers

PMID34916436
PMCPMC8771111
OpenAlexW4200506511

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.