Evidence map›Paper›PMID 34916275›Full record

ReviewBMJ global health2021

Roll-out of HIV pre-exposure prophylaxis: a gateway to mental health promotion.

Daniel J Ikeda, Khameer Kidia, Bruce D Agins, Jessica E Haberer, Alexander C Tsai

Open access · goldAbstract readReview
In one paragraph

Review in BMJ global health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 23 citations in OpenAlex.

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  16. Syndemics and clinical science.Nature medicine · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Daniel J IkedaHarvard Medical School, Boston, Massachusetts, USA daniel_ikeda@hms.harvard.edu.ORCID 0000-0001-7338-0778
Khameer KidiaDivision of Global Health Equity, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Bruce D AginsInstitute for Global Health Sciences, University of California San Francisco, San Francisco, California, USA.
Jessica E HabererCenter for Global Health and Mongan Institute, Massachusetts General Hospital, Boston, Massachusetts, USA.
Alexander C TsaiCenter for Global Health and Mongan Institute, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID 0000-0001-6397-7917
Massachusetts General Hospital · USBrigham and Women's Hospital · USHarvard University · USUniversity of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

HIV remains a pressing global health problem, with 1.5 million new infections reported globally in 2020. HIV pre-exposure prophylaxis (PrEP) can lower the likelihood of HIV acquisition among populations at elevated risk, yet its global roll-out has been discouragingly slow. Psychosocial factors, such as co-occurring mental illness and substance use, are highly prevalent among populations likely to benefit from PrEP, and have been shown to undermine persistence and adherence. In this analysis, we review the high burden of mental health problems among PrEP candidates and contend that inattention to mental health stands to undermine efforts to implement PrEP on a global scale. We conclude that integration of mental health screening and treatment within PrEP scale-up efforts represents an important strategy for maximising PrEP effectiveness while addressing the high burden of mental illness among at-risk populations. As implementers seek to integrate mental health services within PrEP services, efforts to keep access to PrEP as low-threshold as possible should be maintained. Moreover, programmes should seek to implement mental health interventions that are sensitive to local resource constraints and seek to reduce intersecting stigmas associated with HIV and mental illness.

Indexed as

Anti-HIV AgentsHIV InfectionsPre-Exposure ProphylaxisHealth PromotionHumansRisk FactorsAnti-HIV AgentsHIVmental health & psychiatry

Identifiers

PMID34916275
PMCPMC8679108
OpenAlexW4200175073

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.